Avapritinib Clinical Trials

8 recruitingDrug
Phase 24Not Applicable1Phase 41Phase 11

Showing 18 of 8 trials

Recruiting
Phase 2

A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.

Malignant Solid Tumor
Centre Leon Berard455 enrolled10 locationsNCT04116541
Recruiting

A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in Germany

Indolent Systemic Mastocytosis
Blueprint Medicines Corporation80 enrolled8 locationsNCT07255638
Recruiting
Phase 1

Avapritinib With Decitabine in Patients With SM-AHN

Systemic Mastocytosis With an Associated Hematologic Neoplasm
H. Lee Moffitt Cancer Center and Research Institute34 enrolled7 locationsNCT06327685
Recruiting
Phase 2

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+26 more
M.D. Anderson Cancer Center50 enrolled1 locationNCT04771520
Recruiting
Phase 4

Avapritinib Rollover Study

Mastocytosis, Systemic
Blueprint Medicines Corporation60 enrolled7 locationsNCT06748001
Recruiting
Not Applicable

MRD-positive AML Clinical Study

AML, Adult
Institute of Hematology & Blood Diseases Hospital, China120 enrolled1 locationNCT07131059
Recruiting
Phase 2

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

Relapse/RecurrenceAML, ChildhoodRefractory AML+2 more
Children's Hospital of Soochow University50 enrolled12 locationsNCT06316960
Recruiting
Phase 2

Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AML

Acute Myeloid LeukemiaAML, Childhood
Children's Hospital of Soochow University500 enrolled13 locationsNCT06221683