Botensilimab Clinical Trials

14 recruitingDrug
Phase 29Phase 12Phase 32Early Phase 11

Showing 114 of 14 trials

Recruiting
Phase 2

A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma

Locally Advanced Rectal AdenocarcinomaMicrosatellite Stable Rectal Carcinoma
Memorial Sloan Kettering Cancer Center40 enrolled7 locationsNCT06843434
Recruiting
Phase 3

Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma

Colorectal, Cancer
Canadian Cancer Trials Group834 enrolled55 locationsNCT07152821
Recruiting
Phase 2

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Colorectal, CancerLiver MetastasesColorectal Cancer Metastatic
Weill Medical College of Cornell University24 enrolled1 locationNCT06300463
Recruiting
Early Phase 1

Botensilimab, Balstilimab, and SBRT in Colorectal Cancer

Non-MSI-H or pMMR Colorectal Cancer With Liver Metastasis
Massachusetts General Hospital15 enrolled1 locationNCT07128355
Recruiting
Phase 2

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Glioblastoma MultiformeNewly Diagnosed GlioblastomaGlioblastoma, Isocitric Dehydrogenase (IDH)-Wildtype+1 more
Northwestern University25 enrolled1 locationNCT05864534
Recruiting
Phase 3

Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas

Gastric CancerMetastatic CancerAdvanced Cancer+1 more
Centre Leon Berard132 enrolled6 locationsNCT06346197
Recruiting
Phase 1

Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients With KRAS-Mutant Metastatic Colorectal Cancer

Stage IV Colorectal Cancer AJCC v8Metastatic Colorectal Adenocarcinoma
University of Southern California15 enrolled3 locationsNCT06336902
Recruiting
Phase 2

Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)

Colorectal, CancerResectable Colorectal Carcinoma
Gruppo Oncologico del Nord-Ovest197 enrolled1 locationNCT05845450
Recruiting
Phase 2

A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy

Colorectal, CancerRectal Cancer
Memorial Sloan Kettering Cancer Center284 enrolled7 locationsNCT07227636
Recruiting
Phase 2

Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas

Metastatic Soft Tissue SarcomaAdvanced Soft Tissue Sarcoma
University of Colorado, Denver65 enrolled1 locationNCT04028063
Recruiting
Phase 1

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Colorectal, CancerPancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins54 enrolled1 locationNCT06411691
Recruiting
Phase 2

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

Metastatic Gastric AdenocarcinomaMetastatic Gastroesophageal Junction AdenocarcinomaUnresectable Gastric Adenocarcinoma+10 more
Memorial Sloan Kettering Cancer Center37 enrolled7 locationsNCT06251973
Recruiting
Phase 2

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

Metastatic Pancreatic CancerMetastatic Pancreatic Ductal Adenocarcinoma
Benjamin Spieler20 enrolled1 locationNCT06843551
Recruiting
Phase 2

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

Rectal AdenocarcinomaStage III Rectal Cancer AJCC v8Stage IIA Rectal Cancer AJCC v8
City of Hope Medical Center26 enrolled1 locationNCT06780787