Dostarlimab Clinical Trials
24 recruitingDrug
Phase 218Phase 16Phase 33
Showing 1–20 of 24 trials
Recruiting
Phase 2
A Comprehensive Multiomic Biomarker Evaluation Across Two Single-arm Cohorts to Elucidate Mechanisms of Response and Resistance in Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC)
University Health Network, Toronto30 enrolled1 locationNCT07408063
Recruiting
Phase 2
A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer
Neoplasms, Colon
GlaxoSmithKline120 enrolled33 locationsNCT06567782
Recruiting
Phase 1
Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer
Endometrial Cancer
M.D. Anderson Cancer Center21 enrolled1 locationNCT05819892
Recruiting
Phase 2
Phase II Study of Neoadjuvant Dostarlimab in Patients With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer
Colon Cancer Stage III
Universitaire Ziekenhuizen KU Leuven10 enrolled1 locationNCT06830239
Recruiting
Phase 2
Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)
Brain Metastases
M.D. Anderson Cancer Center120 enrolled1 locationNCT05700721
Recruiting
Phase 2
Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery
Endometrial Cancer
Memorial Sloan Kettering Cancer Center62 enrolled7 locationsNCT04774419
Recruiting
Phase 1Phase 2
Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Extracellular Vesicles (EVs), Patient-derived Organoid (PDOs)s and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)
GlaxoSmithKline40 enrolled1 locationNCT06405230
Recruiting
Phase 3
Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Colonic NeoplasmsNeoplasms, Colon
GlaxoSmithKline892 enrolled266 locationsNCT05855200
Recruiting
Phase 2
Dostarlimab, Cisplatin and Etoposide in Combination With Radiotherapy in Sandwich Sequence for Small Cell Neuroendocrine Cervical Carcinoma
Female
Chang Gung Memorial Hospital45 enrolled1 locationNCT07336147
Recruiting
Phase 1Phase 2
Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100
Ovarian Clear Cell Carcinoma
M.D. Anderson Cancer Center21 enrolled1 locationNCT06065462
Recruiting
Phase 2
A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Chinese Participants With Primary Advanced or Recurrent Endometrial Cancer (EC)
Neoplasms, Endometrial
GlaxoSmithKline30 enrolled1 locationNCT07108270
Recruiting
Phase 1
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
Neoplasms
GlaxoSmithKline158 enrolled26 locationsNCT05277051
Recruiting
Phase 2
Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma
Penile Carcinoma
H. Lee Moffitt Cancer Center and Research Institute25 enrolled2 locationsNCT05526989
Recruiting
Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer
Locally Advanced Rectal Cancer (LARC)
National Cancer Institute, Naples50 enrolled2 locationsNCT07269249
Recruiting
Phase 2
Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
Soft Tissue SarcomaPancreatic AdenocarcinomaAdrenocortical Carcinoma+2 more
UNICANCER120 enrolled22 locationsNCT06333314
Recruiting
Phase 1Phase 2
A Study of GSK5733584 in Combination With Anti-cancer Therapies for Advanced Solid Tumors
Tumours, Gynecological
GlaxoSmithKline392 enrolled56 locationsNCT06796907
Recruiting
Phase 3
A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
Neoplasms, Head and Neck
GlaxoSmithKline864 enrolled240 locationsNCT06256588
Recruiting
Phase 2
A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study)
Ovarian NeoplasmsUterine Cervical NeoplasmsEndometrial Neoplasms+3 more
Yonsei University198 enrolled18 locationsNCT06023862
Recruiting
Phase 2
Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers
Colon CancerdMMR Colorectal Cancer
University of Iowa25 enrolled1 locationNCT05239546
Recruiting
Phase 2
DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic Cancer
Pancreas Neoplasms
Hopital Foch35 enrolled5 locationsNCT06757244