Ivonescimab Clinical Trials

36 recruitingDrug
Phase 233Phase 110

Showing 120 of 36 trials

Recruiting
Phase 1Phase 2

A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma

Glioblastoma
M.D. Anderson Cancer Center45 enrolled2 locationsNCT06672575
Recruiting
Phase 1Phase 2

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

Non-small Cell Lung Cancer (NSCLC)Advanced Solid TumorsNSCLC+3 more
Revolution Medicines, Inc.370 enrolled6 locationsNCT07397338
Recruiting
Phase 2

Ivonescimab Alone And With Carboplatin/Pemetrexed For NSCLC

Lung Cancer (Non-Small Cell)Lung Cancer (NSCLC)Lung Cancer Non-Small Cell Cancer (NSCLC)+1 more
Massachusetts General Hospital46 enrolled3 locationsNCT07405190
Recruiting
Phase 1Phase 2

A Study of Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center66 enrolled7 locationsNCT07535437
Recruiting
Phase 2

Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer

TNBC - Triple-Negative Breast CancerEarly Stage Triple-Negative Breast CarcinomaTNBC
Cedars-Sinai Medical Center34 enrolled4 locationsNCT07017673
Recruiting
Phase 2

Ivonescimab for the Treatment of Thymic Cancer

Thymus Carcinoma
Jonsson Comprehensive Cancer Center25 enrolled5 locationsNCT06980077
Recruiting
Phase 2

Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer

Advanced Head and Neck Squamous Cell CarcinomaResectable Head and Neck Squamous Cell CarcinomaStage II Head and Neck Cutaneous Squamous Cell Carcinoma+2 more
University of Michigan Rogel Cancer Center28 enrolled1 locationNCT07094685
Recruiting
Phase 1Phase 2

A Study of YL201 and Ivonescimab (AK112) in Advanced Solid Tumors

Non-small Cell Lung CancerAdvanced Solid TumorsSmall Cell Lung Cancer
MediLink Therapeutics (Suzhou) Co., Ltd.260 enrolled1 locationNCT07208773
Recruiting
Phase 1

A Study of Tepotinib and Ivonescimab in People With Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center16 enrolled7 locationsNCT07619339
Recruiting
Phase 2

Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma

Cutaneous Squamous Cell Carcinoma
M.D. Anderson Cancer Center24 enrolled1 locationNCT06567314
Recruiting
Phase 2

IvoLoC Trial: A Phase II Trial Evaluating the Efficacy of Ivonescimab in Metastatic Endocrine Refractory HR-positive HER2-negative or Triple Negative Invasive Lobular Carcinoma

Metastatic Endocrine RefractoryTriple Negative Invasive Lobular Carcinoma
M.D. Anderson Cancer Center29 enrolled1 locationNCT07229417
Recruiting
Phase 2

Ivonescimab Prior to Surgery for the Treatment of High-Risk Localized Clear Cell Renal Cell Cancer

Stage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8Stage II Renal Cell Cancer AJCC v8+2 more
City of Hope Medical Center31 enrolled1 locationNCT07226544
Recruiting

Mechanism of Enhanced Efficacy of Ivonescimab in Neoadjuvant Therapy for Non-Small Cell Lung Cancer

Neoadjuvant TherapyNon-small Cell Lung CancerImmunotherapy+1 more
Peking University People's Hospital80 enrolled1 locationNCT07359040
Recruiting
Phase 2

A Study of Ivonescimab in People With Leiomyosarcoma

Leiomyosarcoma
Memorial Sloan Kettering Cancer Center20 enrolled7 locationsNCT07516925
Recruiting
Phase 2

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

Breast CancerBreast NeoplasmHER2-negative Breast Cancer+7 more
Fudan University716 enrolled1 locationNCT05582499
Recruiting
Phase 2

Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients

Biliary Tract Cancer
UNICANCER72 enrolled41 locationsNCT06529718
Recruiting
Phase 2

Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
M.D. Anderson Cancer Center90 enrolled1 locationNCT06959550
Recruiting
Phase 1Phase 2

A Study of Ivonescimab in People With Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center36 enrolled7 locationsNCT07594522
Recruiting
Phase 2

Phase II Trial of Ivonescimab in Previously Treated Patients With Advanced Clear Cell Renal Cell Carcinoma

IvonescimabClear Cell Renal Carcinoma
M.D. Anderson Cancer Center40 enrolled1 locationNCT06940518
Recruiting
Phase 1Phase 2

Adapted Guided Stereotactic Body Radiotherapy Combined With Chemotherapy and Enhancement of Novel Drug Ivonescimab for Pancreatic Cancer (ASCEND)

Pancreatic Cancer
Shandong Cancer Hospital and Institute37 enrolled1 locationNCT06844422