Letermovir Clinical Trials

17 recruitingDrug
Phase 35Phase 24Phase 13Phase 43Not Applicable2

Showing 117 of 17 trials

Recruiting
Phase 1

A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

Congenital Cytomegalovirus Infection
National Institute of Allergy and Infectious Diseases (NIAID)12 enrolled10 locationsNCT06118515
Recruiting
Phase 3

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Versus Valaciclovir

Assistance Publique - Hôpitaux de Paris46 enrolled1 locationNCT05446571
Recruiting
Phase 1

A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

Cytomegalovirus Prophylaxis
Merck Sharp & Dohme LLC40 enrolled11 locationsNCT07199465
Recruiting
Phase 1

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

Hematopoietic and Lymphatic System NeoplasmAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+9 more
City of Hope Medical Center46 enrolled3 locationsNCT07020533
Recruiting
Not Applicable

Letermovir Prophylaxis in Children With EBV-Positive T/NK-Cell Lymphoproliferative Disease and Refractory/Relapsed EBV-Associated Hemophagocytic Lymphohistiocytosis

EBV-associated T/NK-cell Lymphoproliferative DiseasesRefractory/Relapsed EBV-related Hemophagocytic LymphohistiocytosisLetermovir
Beijing Children's Hospital80 enrolled1 locationNCT07488728
Recruiting
Phase 3

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm
Children's Oncology Group105 enrolled28 locationsNCT05711667
Recruiting
Phase 4

Combination Letermovir and Standard of Care Antiviral for Enhanced Antiviral Response in Cytomegalovirus Infection in Lung Transplant Recipients

CMVLung Transplant Recipient
University Health Network, Toronto40 enrolled1 locationNCT07235683
Recruiting
Phase 2

Single Arm Pilot Trial of Letermovir for CMV Prophy in CAR T Cell

Cell Therapy
M.D. Anderson Cancer Center36 enrolled1 locationNCT06575374
Recruiting
Phase 3

Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections

Assistance Publique - Hôpitaux de Paris80 enrolled5 locationsNCT06334497
Recruiting
Phase 4

Efficacy and Safety of Leymovir Versus Valganciclovir in Prevention of Cytomegalovirus Infection and Cytomegalovirus Disease in Chinese Kidney Transplant Recipients

Kidney Transplant
First Affiliated Hospital Xi'an Jiaotong University290 enrolled1 locationNCT07266467
Recruiting
Phase 2

Phase II Trials of Letermovir Prophylaxis in Patients With RRMM Undergoing Elranatamab Therapy

Relapsed Refractory Multiple Myeloma (RRMM)
Seoul National University Hospital40 enrolled1 locationNCT06920251
Recruiting
Not Applicable

The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant Recipients

Hematopoietic Cell TransplantCytomegalovirus Cell Mediated Immunity
M.D. Anderson Cancer Center105 enrolled1 locationNCT06639854
Recruiting
Phase 3

Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients

Cytomegalovirus InfectionsKidney Transplant InfectionPancreas Transplant
University of Wisconsin, Madison90 enrolled1 locationNCT06407232
Recruiting
Phase 2Phase 3

Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant

Heart Transplant InfectionCMV ViremiaHeart Transplant Failure and Rejection
Columbia University150 enrolled2 locationsNCT07079735
Recruiting
Phase 2

CMV-TCIP Directed Letermovir Prophylaxis After Allo-SCT

CMV
University of California, Irvine50 enrolled1 locationNCT06453460
Recruiting
Phase 4

Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients

NeutropeniaCytomegalovirus InfectionsInfection in Solid Organ Transplant Recipients+1 more
Tufts Medical Center25 enrolled1 locationNCT05626530
Recruiting

Effect of Letermovir Prophylaxis on CMV-specific Immune Reconstitution Post UCBT

Cytomegalovirus Infection Reactivation
Anhui Provincial Hospital60 enrolled1 locationNCT06441669