Serplulimab Clinical Trials
30 recruitingDrug
Phase 227Phase 12Phase 31Not Applicable1
Showing 1–20 of 30 trials
Recruiting
Phase 2
A Phase II Randomized Trial of Serplulimab With Second-Line Chemo/Targeted Therapy for Early Relapse Colorectal Cancer After Adjuvant Chemotherapy
Colorectal, CancerRelapse
Fudan University40 enrolled1 locationNCT07604909
Recruiting
Phase 2
Serplulimab Monotherapy in Elderly Patients With NSCLC and PD-L1 TPS ≥ 50%
NSCLC (Non-small Cell Lung Cancer)
Tang-Du Hospital60 enrolled1 locationNCT07596121
Recruiting
Phase 2
Neoadjuvant Serplulimab Plus Weekly Paclitaxel and Carboplatin in TNBC (Neo-SERPENT)
Triple-Negative Breast Cancer
RenJi Hospital46 enrolled1 locationNCT07283692
Recruiting
Phase 2
Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After Treatment
Small Cell Lung Cancer
Guangdong Association of Clinical Trials66 enrolled1 locationNCT05957510
Recruiting
Phase 1
Study of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in Participants With Extensive Stage Small-Cell Lung Cancer
Small Cell Lung Cancer
Suzhou Zelgen Biopharmaceuticals Co.,Ltd100 enrolled1 locationNCT07231445
Recruiting
Phase 2Phase 3
Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients
Colorectal, CancerLiver Metastases
Sun Yat-sen University156 enrolled1 locationNCT06280495
Recruiting
Phase 2
SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases
Colorectal CarcinomaOligometastasespMMR+2 more
First Affiliated Hospital of Zhejiang University51 enrolled1 locationNCT06850103
Recruiting
Phase 2
Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer
Locally Advanced Rectal CarcinomapMMRMSS+1 more
Zhejiang University50 enrolled1 locationNCT05731726
Recruiting
Phase 2
Efficacy and Safety of Anti-PD-1, Thymalfasin, and SOX in Neoadjuvant Treatment of cStage III Gastric/Gastroesophageal Junction Adenocarcinoma
Gastric CancerEsophagogastric Junction Adenocarcinoma
Zekuan Xu30 enrolled1 locationNCT06461910
Recruiting
Phase 2
A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCLC
Non-small Cell Lung Cancer
Shanghai Henlius Biotech60 enrolled1 locationNCT07269782
Recruiting
Phase 2
Serplulimab for Locally Advanced Cervical Cancer
Cervical Cancer
Tianjin Medical University Cancer Institute and Hospital216 enrolled1 locationNCT07340489
Recruiting
Phase 2
Serplulimab With Chemoradiotherapy for Postoperative Cervical Cancer With Risk Factors
Cervical Cancers
Tianjin Medical University Cancer Institute and Hospital134 enrolled1 locationNCT06727617
Recruiting
Phase 1Phase 2
A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors
Non-small Cell Lung CancerSolid Tumor Cancer
Shanghai Henlius Biotech105 enrolled3 locationsNCT06848699
Recruiting
Phase 2
Neoadjuvant Chemotherapy Plus Sequential Immune Checkpoint Inhibitor (ICI) Therapy in Locally Advanced Colon Cancer
Colon Cancer
Ruijin Hospital56 enrolled1 locationNCT06368141
Recruiting
Phase 2
Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC
Esophageal Squamous Cell Carcinoma
Fujian Medical University Union Hospital90 enrolled1 locationNCT06601309
Recruiting
Phase 2
Long-course Chemoradiotherapy or Short-course Radiotherapy Combined With CAPOX, PD-1antibody, and COX-2 Inhibitor for MSS Locally Advanced Rectal Cancer (SERRAC)
Neoadjuvant TherapyLocally Advanced Rectal Cancer
Fudan University138 enrolled1 locationNCT07150949
Recruiting
NabPE With or Without Serplulimab for Early-stage HR+/HER2- Breast Cancer.
Breast Cancer Invasive
Henan Cancer Hospital709 enrolled1 locationNCT06781281
Recruiting
Phase 2
Serplulimab Combined With Chemotherapy for Early-stage HR+/HER2- Breast Cancer
HR+/HER2- Breast Cancer
Henan Cancer Hospital357 enrolled1 locationNCT06860529
Recruiting
Phase 2
Sequential Tegafur-gimeracil-oteracil Potassium Capsule (s-1) and Serplulimab Following Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma
Locally Advanced Inoperable Esophageal Squamous Cell Carcinoma
Zhejiang Cancer Hospital37 enrolled1 locationNCT06422858
Recruiting
Phase 2
Phase II Study of Serplulimab Combined with First-Line Targeted Therapy, Chemotherapy, and Radiation in Advanced Colorectal Cancer
Advanced Colorectal CarcinomaImmunotherapy
Fudan University208 enrolled10 locationsNCT06521866