Changi General Hospital

Singapore, Singapore

9 recruiting

Showing 120 of 23 trials

Recruiting
Phase 3

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

Primary Biliary Cholangitis
Gilead Sciences318 enrolled196 locationsNCT06051617
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1152 locationsNCT07064473
Recruiting
Phase 3

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Metabolic Dysfunction-Associated Steatohepatitis
Boehringer Ingelheim1,590 enrolled443 locationsNCT06632457
Recruiting
Phase 3

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Metabolic dysfunction-associated steatohepatitis (MASH)Liver Fibrosis
Boehringer Ingelheim1,800 enrolled524 locationsNCT06632444
Recruiting
Phase 3

The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

Bronchiectasis
Boehringer Ingelheim1,755 enrolled494 locationsNCT06872892
Recruiting
Not Applicable

Left Bundle Branch Area Pacing (LBBAP) PMCF Study

Heart FailureCardiac DiseaseAtrial Fibrillation (AF)+4 more
Abbott Medical Devices200 enrolled13 locationsNCT07217392
Recruiting
Phase 3

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

ObesityOverweightAtherosclerotic Cardiovascular Disease
Amgen12,800 enrolled759 locationsNCT07037433
Recruiting
Not Applicable

Feasibility, Safety and Efficacy of a Predominantly Plant-based Diet in an Asian Population With Chronic Kidney Disease

Diet HabitChronic Kidney Disease stage3Chronic Kidney Disease stage4
Changi General Hospital40 enrolled1 locationNCT07544524
Recruiting
Not Applicable

A Randomized Controlled Trial Comparing Whole Body Vibration Therapy With Usual Care and Usual Care to Improve Muscle Health in Older Adults

SarcopeniaFrailtyAging+3 more
Changi General Hospital40 enrolled1 locationNCT07205133
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

Primary IgA Nephropathy
Hoffmann-La Roche428 enrolled202 locationsNCT05797610
Recruiting

Gut Microbiome and Metabolome in Patients With Gallstone Disease After Surgical and Endoscopic Interventions

Bile Duct DiseasesGallstone Disease
Changi General Hospital65 enrolled1 locationNCT05689255
Recruiting
Phase 3

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

Heart Failure
Novo Nordisk A/S5,600 enrolled1117 locationsNCT05636176
Recruiting

Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis

Cirrhosis and Chronic Liver Disease
Singapore General Hospital2,200 enrolled3 locationsNCT07438288
Recruiting
Not Applicable

Cervical Lymphatico-Venous Bypass for Treatment of Alzheimer's Disease - Proof of Concept Study (CLyVeB-AD-1 Study)

Alzheimer DiseaseAlzheimer's Disease (AD)Dementia Alzheimer Type+2 more
Vincent Tay Khwee Soon10 enrolled1 locationNCT06965062
Recruiting

Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors

CirrhosisPortal HypertensionVarices, Esophageal
Chinese University of Hong Kong375 enrolled8 locationsNCT06549673
Recruiting
Phase 2

Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma

Hepatocellular Carcinoma
National Cancer Centre, Singapore30 enrolled6 locationsNCT05516628
Recruiting

Tissue Sodium Quantification in Patients With Primary Aldosteronism: See Sodium to Treat

HypertensionPrimary AldosteronismHypokalemia
Jens Titze80 enrolled4 locationsNCT06569589
Recruiting
Not Applicable

Tackling Disruptions to Frailty Interventions: Developing Personalized Interventions Targeted for Older Persons With Cardiac Frailty

Cardiovascular Diseases
National Heart Centre Singapore500 enrolled6 locationsNCT05946174
Recruiting
Not Applicable

Addressing Medication Non-adherence in Patients With Poorly Controlled Hypertension Using Urine Mass Spectrometry

HypertensionUncontrolled HypertensionNon-Adherence, Medication
Changi General Hospital100 enrolled1 locationNCT06938633
Recruiting
Not Applicable

OneSTOP (One-Stop Telehealth Obesity Program) for Multidisciplinary Weight Management and Related Comorbidities

HypertensionTelemedicineDyslipidaemia+2 more
Changi General Hospital120 enrolled1 locationNCT06890169