Chris O'Brien Lifehouse
Camperdown, New South Wales, Australia
28 recruiting
Showing 1–20 of 28 trials
Recruiting
Phase 3
Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Eyelid Squamous Cell Carcinoma+17 more
National Cancer Institute (NCI)420 enrolled192 locationsNCT06568172
Recruiting
Phase 1Phase 2
A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors
MTAP-deleted Solid Tumors
Bayer370 enrolled58 locationsNCT06914128
Recruiting
Phase 3
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer400 enrolled383 locationsNCT05253651
Recruiting
Phase 3
A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.
Non-small Cell Lung Cancer
ETOP IBCSG Partners Foundation290 enrolled42 locationsNCT06284317
Recruiting
Phase 2
A Study of BMS-986504 in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion (MountainTAP-9)
Carcinoma, Non-Small Cell Lung
Bristol-Myers Squibb130 enrolled71 locationsNCT06855771
Recruiting
Phase 3
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Non-small Cell Lung CancerNSCLCNSCLC (Advanced Non-small Cell Lung Cancer)+2 more
Revolution Medicines, Inc.420 enrolled129 locationsNCT06881784
Recruiting
Phase 1
A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)
Non-small Cell Lung Cancer
Dizal Pharmaceuticals140 enrolled5 locationsNCT06905197
Recruiting
Phase 1
A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors
Solid TumorsClear Cell Renal Cell Carcinoma
Arcus Biosciences, Inc.362 enrolled29 locationsNCT05536141
Recruiting
Phase 1Phase 2
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
Advanced Lung Cancer
BioNTech SE594 enrolled45 locationsNCT06892548
Recruiting
Phase 3
Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
Endometrial Cancer
Karyopharm Therapeutics Inc276 enrolled217 locationsNCT05611931
Recruiting
Phase 3
Sentinel Node Biopsy in Endometrial Cancer
SurgerySentinel Lymph NodeEndometrial Cancer Stage I
Queensland Centre for Gynaecological Cancer760 enrolled19 locationsNCT04073706
Recruiting
Phase 2
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma
Retroperitoneal Liposarcoma
Australia and New Zealand Sarcoma Association100 enrolled9 locationsNCT07377747
Recruiting
Phase 1Phase 2
A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer
Small Cell Lung CancerNeuroendocrine CarcinomasSolid Tumor Show to Express DLL3
IDEAYA Biosciences208 enrolled39 locationsNCT07174583
Recruiting
Not Applicable
PRIORITY-CONNECT 2 Trial
Colorectal, CancerColorectal Neoplasms
Surgical Outcomes Research Centre (SOuRCe)564 enrolled31 locationsNCT06976710
Recruiting
Phase 1
A Study of DM005 in Patients With Advanced Solid Tumors
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckSolid Carcinoma
Doma Biopharmaceutical(Suzhou)Co., Ltd.136 enrolled6 locationsNCT06515990
Recruiting
Metastatic Leiomyosarcoma Biomarker Protocol
Leiomyosarcoma
University of Michigan Rogel Cancer Center200 enrolled11 locationsNCT05653388
Recruiting
Not Applicable
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
Ovarian CancerBRCA1 Gene MutationBRCA2 Gene Mutation+3 more
University Medical Center Nijmegen3,000 enrolled48 locationsNCT04294927
Recruiting
Personalised Immunotherapy Platform
MelanomaSolid TumorMerkel Cell Carcinoma+2 more
Melanoma Institute Australia1,000 enrolled3 locationsNCT06536257
Recruiting
Phase 1
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
SarcomaNon-small Cell Lung CancerHead and Neck Squamous Cell Carcinoma+9 more
Epkin166 enrolled10 locationsNCT06789172