Imperial College Healthcare NHS Trust

London, United Kingdom

35 recruiting

Showing 120 of 68 trials

Recruiting
Phase 3

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Immune Thrombocytopenic Purpura (ITP)
Takeda150 enrolled108 locationsNCT06948318
Recruiting
Not Applicable

Cryoballoon/Radiofrequency/Pulsed Field Ablation of Atrial Fibrillation Versus Medical Treatment for Heart

Atrial Fibrillation (AF)
University College, London1,200 enrolled24 locationsNCT06505798
Recruiting

Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE)

Oesophageal Cancer
University Hospital Southampton NHS Foundation Trust160 enrolled14 locationsNCT06440174
Recruiting
Phase 1

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Metastatic Colorectal Cancer
Hoffmann-La Roche542 enrolled76 locationsNCT04929223
Recruiting

BPH Global Registry

Benign Prostatic HyperplasiaLower Urinary Tract Symptoms
Société Internationale d'Urologie7,500 enrolled26 locationsNCT05543200
Recruiting
Not Applicable

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Refractory Angina
Shockwave Medical, Inc.380 enrolled95 locationsNCT05102019
Recruiting

Using Multiomics to Define Mechanisms of Rhinovirus-induced Chronic Obstructive Pulmonary Disease Exacerbations to Develop Novel Therapies and Therapeutic Targets

COPD, Chronic Obstructive Pulmonary DiseaseExacerbation of COPDRhinovirus Infection
Imperial College London50 enrolled1 locationNCT07112235
Recruiting
Phase 3

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

Regeneron Pharmaceuticals975 enrolled216 locationsNCT06541704
Recruiting
Phase 3

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Immune Thrombocytopenic Purpura (ITP)
Takeda171 enrolled112 locationsNCT06722235
Recruiting
Phase 3

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer400 enrolled382 locationsNCT05253651
Recruiting
Phase 4

A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies

Breast Cancer
Hoffmann-La Roche320 enrolled28 locationsNCT06274515
Recruiting
Not Applicable

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Heart DiseasesCoronary Artery DiseaseCoronary Artery Bypass Grafting
Weill Medical College of Cornell University2,300 enrolled146 locationsNCT04124120
Recruiting

White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)

Normal Pressure Hydrocephalus
Imperial College London100 enrolled1 locationNCT07103681
Recruiting

Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting

AsthmaVasculitisInflammatory Disease+2 more
Imperial College London120 enrolled1 locationNCT05012033
Recruiting

Cancer Loyalty Card Study 2 (CLOCS-2)

Liver CancerPancreatic CancerOvarian Cancer+7 more
Imperial College London2,900 enrolled1 locationNCT06447064
Recruiting
Phase 3

Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

Polycythemia Vera
Italfarmaco220 enrolled90 locationsNCT06093672
Recruiting
Not Applicable

GRACE: Evaluating Compression Stockings in Patients That Require Extended Duration Pharmacological Thromboprophylaxis

SurgeryVenous Thromboembolism
Imperial College London8,608 enrolled3 locationsNCT06166537
Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma

Pancreatic CancerPDAC - Pancreatic Ductal Adenocarcinoma
Imperial College London1,005 enrolled1 locationNCT05727020
Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR2)

Pancreatic CancerPDAC - Pancreatic Ductal Adenocarcinoma
Imperial College London6,079 enrolled1 locationNCT07243262
Recruiting
Phase 2

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Regeneron Pharmaceuticals95 enrolled26 locationsNCT06421636