Imperial College Healthcare NHS Trust
London, United Kingdom
35 recruiting
Showing 1–20 of 72 trials
Recruiting
Phase 3
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Age related macular degeneration (AMD)Geographic Atrophy (GA)
Regeneron Pharmaceuticals975 enrolled218 locationsNCT06541704
Recruiting
Phase 3
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
MyelofibrosisAnemia
Takeda324 enrolled207 locationsNCT07623161
Recruiting
Phase 1Phase 2
Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
Endometrial CancerRecurrent Ovarian CancerLow Grade Serous Ovarian Cancer+3 more
Regeneron Pharmaceuticals890 enrolled52 locationsNCT03564340
Recruiting
Phase 3
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer400 enrolled366 locationsNCT05253651
Recruiting
Not Applicable
The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study
Aortic Stenosis
University of Leicester2,104 enrolled110 locationsNCT04204915
Recruiting
Phase 1
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Metastatic Colorectal Cancer
Hoffmann-La Roche542 enrolled84 locationsNCT04929223
Recruiting
Phase 1
Development of a Controlled Human Infection Model for Assessment of SARS-CoV-2 Omicron Subvariants
SARS-CoV-2 (COVID-19),
Imperial College London38 enrolled5 locationsNCT07397455
Recruiting
Phase 1Phase 2
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Endometrial CancerAdvanced Solid TumorDiffuse Large B Cell Lymphoma+5 more
Novartis Pharmaceuticals300 enrolled81 locationsNCT04104776
Recruiting
Phase 3
A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
Immune Thrombocytopenic Purpura (ITP)
Takeda150 enrolled109 locationsNCT06948318
Recruiting
Phase 3
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
Immune Thrombocytopenic Purpura (ITP)
Takeda171 enrolled114 locationsNCT06722235
Recruiting
Phase 2
Rescue of Nephrons With ALE.F02 (RENAL-F02)
Glomerulonephritis Rapidly Progressive
Alentis Therapeutics AG80 enrolled51 locationsNCT06047171
Recruiting
Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR2)
Pancreatic CancerPDAC - Pancreatic Ductal Adenocarcinoma
Imperial College London6,079 enrolled1 locationNCT07243262
Recruiting
Phase 4
A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies
Breast Cancer
Hoffmann-La Roche320 enrolled28 locationsNCT06274515
Recruiting
Phase 3
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Atrial FibrillationStrokeBleeding
Icahn School of Medicine at Mount Sinai3,200 enrolled106 locationsNCT04045665
Recruiting
Phase 2
Phase IIa Trial in Participants With Asthma to Evaluate Impact of Intranasal ETH47 on Development of Asthma-related Symptoms Following Rhinovirus Challenge
Asthma (Diagnosis)
Ethris GmbH50 enrolled2 locationsNCT07059767
Recruiting
Not Applicable
Study of Lesion-Specific Invasive Haemodynamic Angina Thresholds
Coronary Artery Disease (CAD)Angina, Stableischaemic heart disease (IHD)
Imperial College London60 enrolled7 locationsNCT07386418
Recruiting
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb1,700 enrolled99 locationsNCT05489705
Recruiting
Phase 2
A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery
Ovarian CancerPeritoneal Carcinomatosis
Oncoinvent Solutions AS114 enrolled10 locationsNCT06504147
Recruiting
Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma
Pancreatic CancerPDAC - Pancreatic Ductal Adenocarcinoma
Imperial College London1,005 enrolled1 locationNCT05727020
Recruiting
Chronic Limb-Threatening Ischemia Treated With Intravascular Lithotripsy Observational Study
Chronic Limb Threatening Ischemia
Cardiovascular and Interventional Radiological Society of Europe400 enrolled39 locationsNCT06149650