Imperial College Healthcare NHS Trust

London, United Kingdom

35 recruiting

Showing 120 of 69 trials

Recruiting

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb1,700 enrolled99 locationsNCT05489705
Recruiting
Phase 3

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Immune Thrombocytopenic Purpura (ITP)
Takeda171 enrolled114 locationsNCT06722235
Recruiting
Phase 3

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Immune Thrombocytopenic Purpura (ITP)
Takeda150 enrolled108 locationsNCT06948318
Recruiting
Phase 4

A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies

Breast Cancer
Hoffmann-La Roche320 enrolled28 locationsNCT06274515
Recruiting
Phase 3

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer400 enrolled381 locationsNCT05253651
Recruiting
Phase 3

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

Age related macular degeneration (AMD)Geographic Atrophy (GA)
Regeneron Pharmaceuticals975 enrolled216 locationsNCT06541704
Recruiting
Phase 1

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Metastatic Colorectal Cancer
Hoffmann-La Roche542 enrolled82 locationsNCT04929223
Recruiting
Phase 2

A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery

Ovarian CancerPeritoneal Carcinomatosis
Oncoinvent Solutions AS114 enrolled10 locationsNCT06504147
Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma

Pancreatic CancerPDAC - Pancreatic Ductal Adenocarcinoma
Imperial College London1,005 enrolled1 locationNCT05727020
Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR2)

Pancreatic CancerPDAC - Pancreatic Ductal Adenocarcinoma
Imperial College London6,079 enrolled1 locationNCT07243262
Recruiting

Chronic Limb-Threatening Ischemia Treated With Intravascular Lithotripsy Observational Study

Chronic Limb Threatening Ischemia
Cardiovascular and Interventional Radiological Society of Europe400 enrolled39 locationsNCT06149650
Recruiting
Not Applicable

Surgical vs Transcatheter Aortic Valve Replacement in YOUNG Patients

Symptomatic Severe Aortic Stenosis
Ceric Sàrl1,180 enrolled49 locationsNCT06861361
Recruiting
Phase 1Phase 2

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

Endometrial CancerRecurrent Ovarian CancerLow Grade Serous Ovarian Cancer+3 more
Regeneron Pharmaceuticals890 enrolled52 locationsNCT03564340
Recruiting
Not Applicable

Artificial Intelligence Delivered Cardiac Magnetic Resonance - Prospective Validation

Cardiovascular DiseasesHealthy Volunteers
Imperial College London150 enrolled1 locationNCT06061822
Recruiting
Not Applicable

Cryoballoon/Radiofrequency/Pulsed Field Ablation of Atrial Fibrillation Versus Medical Treatment for Heart

Atrial Fibrillation (AF)
University College, London1,200 enrolled24 locationsNCT06505798
Recruiting

Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE)

Oesophageal Cancer
University Hospital Southampton NHS Foundation Trust160 enrolled14 locationsNCT06440174
Recruiting

BPH Global Registry

Benign Prostatic HyperplasiaLower Urinary Tract Symptoms
Société Internationale d'Urologie7,500 enrolled26 locationsNCT05543200
Recruiting
Not Applicable

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Refractory Angina
Shockwave Medical, Inc.380 enrolled95 locationsNCT05102019
Recruiting

Using Multiomics to Define Mechanisms of Rhinovirus-induced Chronic Obstructive Pulmonary Disease Exacerbations to Develop Novel Therapies and Therapeutic Targets

COPD, Chronic Obstructive Pulmonary DiseaseExacerbation of COPDRhinovirus Infection
Imperial College London50 enrolled1 locationNCT07112235
Recruiting
Not Applicable

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Heart DiseasesCoronary Artery DiseaseCoronary Artery Bypass Grafting
Weill Medical College of Cornell University2,300 enrolled146 locationsNCT04124120