Imperial College Healthcare NHS Trust
London, United Kingdom
35 recruiting
Showing 1–20 of 35 trials
Recruiting
Phase 3
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer400 enrolled383 locationsNCT05253651
Recruiting
Phase 2
A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery
Ovarian CancerPeritoneal Carcinomatosis
Oncoinvent Solutions AS114 enrolled10 locationsNCT06504147
Recruiting
Phase 4
A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies
Breast Cancer
Hoffmann-La Roche320 enrolled28 locationsNCT06274515
Recruiting
Phase 2
A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population
Breast Cancer
MedSIR976 enrolled41 locationsNCT05708235
Recruiting
Phase 1
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Metastatic Colorectal Cancer
Hoffmann-La Roche542 enrolled73 locationsNCT04929223
Recruiting
Not Applicable
Avoidance of Insulin-induced Lipohypertophy in People With Diabetes Using Ultrasound Scanning Within Diabetes Clinics
Type 1 Diabetes (T1D)Type 2 Diabetes, Insulin Requiring
Imperial College London50 enrolled1 locationNCT06782568
Recruiting
Phase 3
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Atrial FibrillationStrokeBleeding
Icahn School of Medicine at Mount Sinai3,200 enrolled101 locationsNCT04045665
Recruiting
Cancer Loyalty Card Study 2 (CLOCS-2)
Liver CancerPancreatic CancerOvarian Cancer+7 more
Imperial College London2,900 enrolled1 locationNCT06447064
Recruiting
Phase 1Phase 2
A Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia (CARDINAL)
Chronic Myeloid LeukemiaChronic Myeloid Leukemia, Chronic Phase
Terns, Inc.180 enrolled54 locationsNCT06163430
Recruiting
Not Applicable
Automated Insulin Delivery in Adults With Advanced Kidney Disease
Diabetes MellitusChronic Kidney Diseases
Imperial College London12 enrolled1 locationNCT06463483
Recruiting
Phase 1Phase 2
Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
Endometrial CancerRecurrent Ovarian CancerLow Grade Serous Ovarian Cancer+3 more
Regeneron Pharmaceuticals890 enrolled51 locationsNCT03564340
Recruiting
Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR2)
Pancreatic CancerPDAC - Pancreatic Ductal Adenocarcinoma
Imperial College London6,079 enrolled1 locationNCT07243262
Recruiting
Not Applicable
Cryoballoon/Radiofrequency/Pulsed Field Ablation of Atrial Fibrillation Versus Medical Treatment for Heart
Atrial Fibrillation (AF)
University College, London1,200 enrolled14 locationsNCT06505798
Recruiting
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb1,600 enrolled99 locationsNCT05489705
Recruiting
Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma
Pancreatic CancerPDAC - Pancreatic Ductal Adenocarcinoma
Imperial College London1,005 enrolled1 locationNCT05727020
Recruiting
Not Applicable
The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study
Aortic Stenosis
University of Leicester2,844 enrolled110 locationsNCT04204915
Recruiting
Phase 1Phase 2
Modi-1 Moditope in Breast, Head and Neck, Ovarian, or Renal Cancer
Triple-Negative Breast CancerSquamous Cell Carcinoma of the Head and NeckRenal Cell Cancer+1 more
Scancell Ltd168 enrolled16 locationsNCT05329532
Recruiting
Phase 1Phase 2
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Endometrial CancerAdvanced Solid TumorDiffuse Large B Cell Lymphoma+5 more
Novartis Pharmaceuticals275 enrolled60 locationsNCT04104776
Recruiting
UK Heart Failure With Preserved Ejection Fraction
Heart Failure With Preserved Ejection Fraction (HFpEF)
Manchester University NHS Foundation Trust10,000 enrolled26 locationsNCT05441839
Recruiting
Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms
Oesophageal CancerOesophageal Squamous Cell Carcinoma
Imperial College London518 enrolled13 locationsNCT06169163