RecruitingNCT06440174

Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE)

Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE): a Multi-methods Study


Sponsor

University Hospital Southampton NHS Foundation Trust

Enrollment

160 participants

Start Date

Jun 27, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This is an observational trial that will look at patients undergoing endoscopic ultrasound (EUS) in patients with oesophageal cancer and to determine the proportion of cases in which EUS changes disease management in these patients.


Eligibility

Min Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This study looks at how often and why doctors use endoscopic ultrasound (EUS) — a procedure that uses sound waves from inside the throat to see detailed images of the esophagus and nearby organs — in patients newly diagnosed with esophageal cancer, to understand how its use varies across different hospitals. **You may be eligible if...** - You are 16 years old or older - You have been newly diagnosed with esophageal cancer (confirmed by biopsy) - You have been referred for an EUS examination as part of your standard care - Your cancer is in the esophagus or at the junction where the esophagus meets the stomach **You may NOT be eligible if...** - You have a different type of esophageal cancer not included in the study - You cannot consent to participation - Your clinical situation makes participation unsuitable Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREendoscopic ultrasound

EUS is an invasive procedure combining upper gastrointestinal endoscopy with ultrasonography. An ultrasound probe located at the end of the endoscope allows direct visualisation of the oesophageal wall layers and adjacent tissues providing local assessment of the depth of tumour invasion and lymph nodes. This assessment informs local tumour (T-) and node (N-) staging which are important prognostic indicators of survival. Patients undergoing EUS require sedation and there are risks of complication. EUS is a specialist investigation requiring many years of dedicated training to perform competently.


Locations(14)

Cwm Taf UHB

Abercynon, United Kingdom

Royal Bournemouth Hospital

Bournemouth, United Kingdom

Cambridge University NHS Foundation Trust

Cambridge, United Kingdom

Cardiff and Vale UHB

Cardiff, United Kingdom

Velindre University NHS Trust

Cardiff, United Kingdom

Glasgow Royal Infirmary

Glasgow, United Kingdom

Castle Hill Hospital

Hull, United Kingdom

Guy's and St Thomas' NHS Foundation Trust

London, United Kingdom

Imperial College Healthcare NHS Trust

London, United Kingdom

Queen's Medical Centre, Nottingham

Nottingham, United Kingdom

Salford Royal Hospital

Salford, United Kingdom

University Hospital Southampton

Southampton, United Kingdom

Singleton Hospital, Swansea

Swansea, United Kingdom

Royal Cornwall Hospital

Truro, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT06440174


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