Oxford University Hospitals NHS Foundation Trust

Oxford, United Kingdom

26 recruiting

Showing 120 of 26 trials

Recruiting
Phase 2

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
Nurix Therapeutics, Inc.100 enrolled18 locationsNCT07221500
Recruiting
Phase 1

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Diffuse Large B-Cell Lymphoma (DLBCL)Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)+6 more
Nurix Therapeutics, Inc.572 enrolled62 locationsNCT05131022
Recruiting
Phase 1

A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

B-cell Non Hodgkin LymphomaRefractory B-Cell Non-Hodgkin LymphomaRelapsed B-Cell Non Hodgkin Lymphoma
ADC Therapeutics S.A.200 enrolled42 locationsNCT04970901
Recruiting
Not Applicable

The Fourth Left Atrial Appendage Occlusion Study

Atrial FibrillationStroke, IschemicSystemic Embolism
Hamilton Health Sciences Corporation4,000 enrolled127 locationsNCT05963698
Recruiting
Phase 3

Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)

Leiomyosarcoma
PharmaMar450 enrolled94 locationsNCT06088290
Recruiting

Placental Biology in Health and Disease

PregnancyPre-EclampsiaFetal Growth Restriction (FGR)+3 more
University of Oxford360 enrolled1 locationNCT07470320
Recruiting
Phase 3

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

Carcinoid TumorCarcinoid Tumor of PancreasCarcinoid Tumor of Liver+6 more
Crinetics Pharmaceuticals Inc.141 enrolled43 locationsNCT07087054
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Parkinson's Disease
Hoffmann-La Roche900 enrolled66 locationsNCT07174310
Recruiting
Phase 1Phase 2

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

Head and Neck Squamous Cell Carcinoma (HNSCC)Non-small Cell Lung Cancer (NSCLC)Triple Negative Breast Cancer(TNBC)+3 more
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.230 enrolled12 locationsNCT05985655
Recruiting
Phase 3

A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype

Lymphoma
SecuraBio124 enrolled43 locationsNCT06522737
Recruiting
Phase 1

A Study of MGC026 in Participants With Advanced Solid Tumors

Breast CancerColorectal, CancerGastric Cancer+19 more
MacroGenics250 enrolled12 locationsNCT06242470
Recruiting
Not Applicable

Oxford Pleural Embolisation Trial

Lung CancerLung Metastases
Oxford University Hospitals NHS Trust106 enrolled1 locationNCT06651658
Recruiting

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

Aortic Valve Stenosis
The Leeds Teaching Hospitals NHS Trust550 enrolled53 locationsNCT06557798
Recruiting
Phase 3

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Atrial FibrillationStrokeBleeding
Icahn School of Medicine at Mount Sinai3,200 enrolled101 locationsNCT04045665
Recruiting
Not Applicable

A Prospective Randomised Study of Treatment Selection Based on Epigenetic Markers Versus Standard of Care Treatment Selection in Adults With CROHN's Disease

Crohn Disease (CD)
Alimentiv Inc.378 enrolled30 locationsNCT07363044
Recruiting
Phase 1Phase 2

A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma

MelanomaAdvanced CancerSolid Tumor+1 more
NuCana plc135 enrolled9 locationsNCT03829254
Recruiting

Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study

Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
University Hospitals Coventry and Warwickshire NHS Trust100 enrolled6 locationsNCT06579443
Recruiting

A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis

Colitis Ulcerative
Pfizer360 enrolled31 locationsNCT06294925
Recruiting
Not Applicable

The Dragon PLC Trial (DRAGON-PLC)

CholangiocarcinomaHepatocellular Carcinoma (HCC)Primary Liver Cancer
Maastricht University358 enrolled55 locationsNCT06914648
Recruiting

DOLCE: Determining the Impact of Optellum's Lung Cancer Prediction Solution

Lung CancerPulmonary Nodule, SolitaryAI (Artificial Intelligence)+1 more
Nottingham University Hospitals NHS Trust2,000 enrolled10 locationsNCT05389774