Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
84 recruiting
Showing 1–20 of 159 trials
Recruiting
Phase 3
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Breast Cancer
Hoffmann-La Roche450 enrolled226 locationsNCT06790693
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
Metastatic Breast Cancer
Hoffmann-La Roche230 enrolled192 locationsNCT05894239
Recruiting
Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset
Premature BirthInfant, Extremely PrematureObstetric Labor, Premature+2 more
The University of Texas Health Science Center, Houston5,000 enrolled51 locationsNCT05685745
Recruiting
Phase 3
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Kidney Disease, Chronic
Boehringer Ingelheim11,000 enrolled452 locationsNCT06531824
Recruiting
Phase 2Phase 3
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
Glioblastoma
Global Coalition for Adaptive Research2,250 enrolled63 locationsNCT03970447
Recruiting
Not Applicable
LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)
Acute Kidney InjuryDialysis; Complications
University of Alberta100 enrolled9 locationsNCT06446739
Recruiting
Phase 3
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Gilead Sciences695 enrolled205 locationsNCT06801834
Recruiting
Not Applicable
Using Cannabis to Treat Restless Legs Syndrome
Restless Leg Syndrome (RLS)
Sunnybrook Health Sciences Centre30 enrolled2 locationsNCT06863740
Recruiting
Not Applicable
Oropharyngeal Exercises to Treat Obstructive Sleep Apnea
Obstructive Sleep Apnea
Sunnybrook Health Sciences Centre45 enrolled1 locationNCT05678088
Recruiting
Not Applicable
Randomization of Single vs Multiple Arterial Grafts
Heart DiseasesCoronary Artery Disease
Weill Medical College of Cornell University4,300 enrolled59 locationsNCT03217006
Recruiting
Not Applicable
The Multicentre Selective Lymphadenectomy Trial - 3
Cutaneous Melanoma, Stage III
Melanoma Institute Australia1,500 enrolled7 locationsNCT07049276
Recruiting
Not Applicable
Liberation From Mechanical Ventilation Using Extubation Advisor Decision Support
Airway Extubation
Ottawa Hospital Research Institute200 enrolled12 locationsNCT05506904
Recruiting
Phase 1Phase 2
A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
Metastatic Breast CancerLocally Advanced Breast CancerUnresectable Breast Carcinoma
BioNTech SE380 enrolled39 locationsNCT06827236
Recruiting
Phase 1
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Breast NeoplasmsColorectal NeoplasmsProstate Neoplasm+2 more
Eli Lilly and Company421 enrolled28 locationsNCT07114601
Recruiting
Phase 3
AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia
Community-acquired Pneumonia
University of Manitoba4,000 enrolled64 locationsNCT05848713
Recruiting
Phase 2
Accelerated dTMS Smoking Cessation
Tobacco Use DisorderAddiction Nicotine
Waypoint Centre for Mental Health Care40 enrolled2 locationsNCT07292883
Recruiting
Not Applicable
Type 1 Diabetes Virtual Self-management Education and Support
Type1diabetes
Unity Health Toronto580 enrolled9 locationsNCT05756829
Recruiting
Not Applicable
Functional Outcomes and Control Using Synchron BCI - Canada
Neurologic DisorderALSMotor Neuron Disease
Synchron, Inc.10 enrolled2 locationsNCT07446114
Recruiting
Phase 2Phase 3
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Agitation Associated With Alzheimer's Disease Dementia
Exciva GmbH300 enrolled14 locationsNCT07284472
Recruiting
Phase 3
JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer
Non-small Cell Lung Cancer
University of Texas Southwestern Medical Center272 enrolled50 locationsNCT02468024