RecruitingNot ApplicableNCT05079464

Exercise as a Primer for Brain Stimulation in Vascular Cognitive Impairment No Dementia (VCIND)

Exercise as a Primer for Excitatory Stimulation Study in Vascular Cognitive Impairment No Dementia (EXPRESS-V)


Sponsor

Sunnybrook Health Sciences Centre

Enrollment

64 participants

Start Date

Nov 22, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

People with vascular conditions are at risk of having memory problems, and these memory problems increase the risk for further cognitive decline. Brain stimulation has been used to improve mood and memory. Transcranial direct current stimulation (tDCS) is believed to work best on brain cells that are active or "primed" before stimulation. The purpose of this study is to compare the effects of exercise and tDCS on memory performance in patients who have completed cardiac rehabilitation and are at risk of cognitive decline.


Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Exercise, Sham stimulation, and others for people with mild cognitive impairment and vascular cognitive impairment. The study is currently recruiting participants at 1 location. People eligible for this study include aged 50 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERtDCS

All participants randomized to tDCS will receive active tDCS

OTHERExercise

Participants will exercise at Toronto Rehab.

OTHERSham stimulation

The same procedure for tDCS will be used for the sham condition, except without active current.

OTHERTreatment as usual

Exercise education/ treatment as usual will include routine advice about physical activity.


Locations(1)

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada

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NCT05079464


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