Universitätsklinikum Bonn

Bonn, Germany

25 recruiting

Showing 120 of 47 trials

Recruiting
Phase 3

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Multiple Myeloma
Pfizer492 enrolled270 locationsNCT06152575
Recruiting
Phase 3

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Heart FailureHeart Failure With Reduced Ejection Fraction
Cytokinetics1,800 enrolled199 locationsNCT06736574
Recruiting
Phase 3

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Dravet Syndrome
Longboard Pharmaceuticals160 enrolled102 locationsNCT06660394
Recruiting
Phase 3

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Relapsed or Refractory Multiple Myeloma
Celgene810 enrolled266 locationsNCT05519085
Recruiting
Not Applicable

Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy

Atrial FibrillationIschemic Stroke
Insel Gruppe AG, University Hospital Bern482 enrolled30 locationsNCT05976685
Recruiting
Phase 3

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Ovarian NeoplasmsNeoplasm MetastasisFallopian Tube Neoplasms+1 more
Eli Lilly and Company1,630 enrolled266 locationsNCT07213804
Recruiting
Phase 3

Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL

Hospital-Acquired PneumoniaCommunity-acquired PneumoniaVentilator associated pneumonia+2 more
Jena University Hospital616 enrolled28 locationsNCT06134492
Recruiting
Phase 3

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

Patients With Non-small-cell Lung Cancer
OSE Immunotherapeutics363 enrolled207 locationsNCT06472245
Recruiting
Phase 3

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer MetastaticNon-Small-Cell Lung CarcinomaNon-small Cell Carcinoma
Pfizer680 enrolled402 locationsNCT07144280
Recruiting
Phase 3

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer
Celgene960 enrolled281 locationsNCT06764485
Recruiting
Phase 3

A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis

Plaque Psoriasis
Takeda110 enrolled40 locationsNCT07250802
Recruiting

Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloidosis Diagnosis

Transthyretin Cardiac Amyloidosis
Idoven 1903 S.L.2,200 enrolled8 locationsNCT06978660
Recruiting
Phase 3

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Non-small Cell Lung Cancer
Bristol-Myers Squibb1,000 enrolled320 locationsNCT06561386
Recruiting

Multicenter Study for the Validation of Willem AI: Aortic StenoSis Early Diagnosis With AI-electrocardiogram Study

Aortic Stenosis
Idoven 1903 S.L.5,000 enrolled2 locationsNCT07479992
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

Von Willebrand Disease, Type 3
Hoffmann-La Roche75 enrolled28 locationsNCT06998524
Recruiting
Not Applicable

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial

Mitral Regurgitation
Medtronic Cardiovascular400 enrolled37 locationsNCT05496998
Recruiting
Phase 3

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals320 enrolled114 locationsNCT06719141
Recruiting
Phase 2

Phase II Study Evaluating Ivosidenib Maintenance After SOC Adjuvant Chemotherapy in Curative mIDH1 Cholangiocarcinoma

CholangiocarcinomaIDH Mutation
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest40 enrolled12 locationsNCT07260175
Recruiting
Phase 3

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis (FAP)
Rapamycin Holdings Inc.168 enrolled29 locationsNCT06950385
Recruiting
Not Applicable

A Comparison of Two Psychotherapy Programs in Persistently Depressed Treatment-Resistant Inpatients

Treatment Resistant DepressionPersistent Depressive Disorder
University of Greifswald396 enrolled8 locationsNCT04996433