University Health Network

Toronto, Ontario, Canada

54 recruiting

Showing 120 of 115 trials

Recruiting
Phase 1

GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours

Triple-Negative Breast CancerRenal Cell CarcinomaAlveolar Soft Part Sarcoma
Canadian Cancer Trials Group30 enrolled2 locationsNCT07297667
Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

MelanomaNon-small Cell Lung CancerThyroid Cancer+2 more
Pfizer267 enrolled40 locationsNCT05355701
Recruiting
Phase 2

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

Prostate Cancer
University of British Columbia315 enrolled9 locationsNCT04812366
Recruiting
Phase 3

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

Clostridium Difficile Infection RecurrenceClostridium DifficileClostridioides Difficile Infection+7 more
Vedanta Biosciences, Inc.852 enrolled215 locationsNCT06237452
Recruiting
Phase 1

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

Carcinoma, Non-Small Cell LungGastroesophageal Junction AdenocarcinomaStomach Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer914 enrolled48 locationsNCT06131840
Recruiting
Phase 1

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

Gastric CancerEndometrial CancerHepatocellular Carcinoma+5 more
Seagen, a wholly owned subsidiary of Pfizer714 enrolled62 locationsNCT05208762
Recruiting

Pancreatic Cancer Early Detection Consortium

Pancreatic Ductal AdenocarcinomaPancreas CancerGenetic Predisposition+1 more
Arbor Research Collaborative for Health20,000 enrolled60 locationsNCT04970056
Recruiting
Phase 2

Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer

Ovarian Cancer
Canadian Cancer Trials Group60 enrolled6 locationsNCT04918186
Recruiting
Not Applicable

Cannabinoids for Osteoarthritis Pain Effectiveness Trial

osteoarthritis of Knee.Osteoarthritis, Hip
University Health Network, Toronto100 enrolled3 locationsNCT06878417
Recruiting
Phase 2

A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity - Substudy B: For Continued Treatment (+/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies

Cancer
Canadian Cancer Trials Group60 enrolled11 locationsNCT03847649
Recruiting
Phase 2

Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

Mantle Cell Lymphoma
Canadian Cancer Trials Group40 enrolled3 locationsNCT07341191
Recruiting
Phase 3

Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer

Advanced Head and Neck Cancer
Canadian Cancer Trials Group196 enrolled9 locationsNCT06641791
Recruiting
Not Applicable

STRatIfication of Vulvar SCC by HPV and p53 Status to Guide Excision

Vulvar Squamous Cell Carcinoma
Canadian Cancer Trials Group249 enrolled11 locationsNCT06358469
Recruiting
Phase 3

Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful Non-Spine Bone Metastases

Cancer, Metastatic
Canadian Cancer Trials Group230 enrolled9 locationsNCT06391242
Recruiting
Phase 2

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

Endometrial Cancer
Canadian Cancer Trials Group393 enrolled114 locationsNCT05640999
Recruiting
Phase 2

STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma
Canadian Cancer Trials Group140 enrolled12 locationsNCT06880523
Recruiting

An Innovative Master Platform for Clinical Trials in Mood Disorders

Depressive DisorderMood DisordersBipolar and Related Disorders
St. Joseph's Healthcare Hamilton2,200 enrolled9 locationsNCT06408012
Recruiting
Not Applicable

Prospective Reduction Of Transplant Complications Through Enhanced Preservation Therapy to Prevent Primary Graft Dysfunction

Primary Graft Dysfunction
University Health Network, Toronto50 enrolled1 locationNCT07230886
Recruiting

Predictors of Relapse in Major Depressive Disorder (PERFORM-D)

Major Depressive Disorder (MDD)
Abraham Nunes252 enrolled9 locationsNCT06746155
Recruiting
Not Applicable

Fecal Microbiota Transplantation in Patients Undergoing Chimeric Antigen Receptor T-cell Therapy and Allogeneic Stem Cell Transplant: A Pilot Study

Lymphoma Receiving CAR-T Therapy
University Health Network, Toronto20 enrolled1 locationNCT07509450