University Health Network

Toronto, Ontario, Canada

54 recruiting

Showing 120 of 54 trials

Recruiting
Phase 1Phase 2

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaMixed Phenotype Acute Leukemia+2 more
Syndax Pharmaceuticals447 enrolled57 locationsNCT04065399
Recruiting
Not Applicable

Theta-Burst Stimulation for Bipolar Depression

Bipolar DisorderBipolar DepressionTreatment- Resistant Bipolar Disorder+1 more
Centre for Addiction and Mental Health124 enrolled2 locationsNCT06370988
Recruiting
Phase 1

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

Carcinoma, Non-Small Cell LungGastroesophageal Junction AdenocarcinomaStomach Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer914 enrolled43 locationsNCT06131840
Recruiting
Phase 2

IVIM & OLINK in Sarcoma

Soft Tissue Sarcoma
University Health Network, Toronto145 enrolled1 locationNCT05950594
Recruiting
Phase 2

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

Endometrial Cancer
Canadian Cancer Trials Group393 enrolled100 locationsNCT05640999
Recruiting
Phase 2Phase 3

Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer

Lung Cancer
Canadian Cancer Trials Group230 enrolled10 locationsNCT04093167
Recruiting
Not Applicable

STRatIfication of Vulvar SCC by HPV and p53 Status to Guide Excision

Vulvar Squamous Cell Carcinoma
Canadian Cancer Trials Group249 enrolled10 locationsNCT06358469
Recruiting
Phase 3

Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma

Colorectal, Cancer
Canadian Cancer Trials Group834 enrolled12 locationsNCT07152821
Recruiting
Phase 3

Duration of Anti-PD-1 Therapy in Metastatic Melanoma

Unresectable/Metastatic Melanoma
Canadian Cancer Trials Group614 enrolled30 locationsNCT02821013
Recruiting

Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive Impairment

Mild Cognitive Impairment (MCI)Major Depressive Disorder, RemittedHealthy Controls Group - Age and Sex-matched
Centre for Addiction and Mental Health150 enrolled3 locationsNCT06780917
Recruiting
Phase 2

Brain Imaging Biomarkers in Patients With Brain Metastasis

Brain Metastases, Adult
University Health Network, Toronto90 enrolled1 locationNCT04197297
Recruiting
Not Applicable

Consolidative Use of Radiotherapy to Block Oligoprogression in Patients With Metastatic Melanoma

Metastatic MelanomaOligoProgressive Metastatic Disease
University Health Network, Toronto52 enrolled1 locationNCT07112170
Recruiting
Phase 2

Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)

Advanced Solid TumorsMultiple MyelomaLymphoma, Non-Hodgkin
Canadian Cancer Trials Group720 enrolled10 locationsNCT03297606
Recruiting
Phase 4

Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

Major Depressive Disorder
Nova Scotia Health Authority400 enrolled7 locationsNCT05017311
Recruiting
Phase 1

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

Gastric CancerEndometrial CancerHepatocellular Carcinoma+5 more
Seagen, a wholly owned subsidiary of Pfizer714 enrolled61 locationsNCT05208762
Recruiting
Phase 2

Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer

Ovarian Cancer
Canadian Cancer Trials Group60 enrolled7 locationsNCT04918186
Recruiting
Phase 2

Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma

Non-Hodgkin Lymphoma
Canadian Cancer Trials Group30 enrolled8 locationsNCT05998642
Recruiting
Phase 2

Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer

Breast Cancer
Canadian Cancer Trials Group484 enrolled10 locationsNCT05601440
Recruiting
Phase 2

LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint Blockade in Advanced Melanoma

Melanoma
Canadian Cancer Trials Group128 enrolled14 locationsNCT06623461
Recruiting
Phase 3

Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes

Metastatic Prostate CancerMetastatic Castration-resistant Prostate Cancer
Canadian Cancer Trials Group236 enrolled14 locationsNCT06439225