RecruitingPhase 2Phase 3NCT06721949

Taurine Supplementation in Long COVID

Taurine Supplementation as a Novel Therapeutic Approach for Neurocognitive Symptoms in Long COVID


Sponsor

University of Alberta

Enrollment

300 participants

Start Date

Nov 18, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The COVID-19 pandemic has swept across the globe, affecting millions of individuals with varying degrees of severity. While many individuals recover from the acute phase of the infection, a significant proportion continue to experience persistent and debilitating symptoms long after the initial SARS-CoV-2 infection. This condition, known as Long COVID (LC) or sometimes referred to as Post-COVID Condition (PCC) or post-acute sequelae of COVID-19, has emerged as a complex multisystemic condition and challenging health issue, affecting approximately 10% of COVID-19 patients. Various symptoms characterize LC, including fatigue, sleep disturbances, cognitive impairment, and mood disturbances. Some of the symptoms are shared with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) - a condition marked by debilitating fatigue and a host of other symptoms without precise biomarkers or objective tests for diagnosis. Effective LC treatments remain elusive and LC patients continue to grapple with persistent symptoms that significantly impact their quality of life. Given the lack of effective treatments, it is imperative to explore novel therapeutic approaches that may alleviate the suffering of this patient population.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called Taurine for people with long covid. The study is currently recruiting participants at 5 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTaurine

Taurine is a naturally occurring amino sulfonic acid commonly found in the body. It is marketed as a natural health product/supplement and plays an important role in the body.

DRUGPlacebo

The placebo capsule is visually identical to the taurine capsule.


Locations(5)

University of Alberta Hospital, Kaye Edmonton Clinic

Edmonton, Alberta, Canada

BC Women's Hospital

Vancouver, British Columbia, Canada

University Health Network

Toronto, Ontario, Canada

Institut de recherches cliniques de Montréal

Montreal, Quebec, Canada

Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre hospitalier universitaire de Sherbrooke

Sherbrooke, Quebec, Canada

View Full Details on ClinicalTrials.gov

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NCT06721949


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