University Medical Center Utrecht

Utrecht, Netherlands

28 recruiting

Showing 120 of 28 trials

Recruiting
Phase 3

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuriaChildren
Bayer100 enrolled178 locationsNCT05457283
Recruiting
Phase 1

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Diffuse Large B-Cell Lymphoma (DLBCL)Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)+6 more
Nurix Therapeutics, Inc.572 enrolled62 locationsNCT05131022
Recruiting
Phase 1Phase 2

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

Non-small Cell Lung Cancer (NSCLC)KRAS, NRAS, HRAS-mutated NSCLCKRAS G12C-mutated Solid Tumors, Lung Cancer+2 more
Revolution Medicines, Inc.616 enrolled89 locationsNCT06162221
Recruiting
Not Applicable

EREctile Function Preservation for Prostate Cancer Radiation Therapy (ERECT)

Prostate CancerErectile Dysfunction Following Radiation Therapy
UMC Utrecht70 enrolled1 locationNCT04861194
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting

Utrecht Prostate Cohort for Cancer Treatment Intervention Studies and Long-term Evaluation

Prostate Cancer
UMC Utrecht1,500 enrolled2 locationsNCT04228211
Recruiting
Phase 3

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817
Recruiting
Phase 1

A Study of SNDX-5613 in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias

Acute Myeloid Leukemias
Syndax Pharmaceuticals76 enrolled46 locationsNCT06226571
Recruiting
Phase 3

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Non-small Cell Lung CancerAnaplastic Lymphoma Kinase-positive
Nuvalent Inc.450 enrolled112 locationsNCT06765109
Recruiting

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

Congenital Heart DiseaseAdult Congenital Heart DiseaseSystemic Right Ventricle+5 more
Leiden University Medical Center400 enrolled11 locationsNCT06932081
Recruiting
Phase 3

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuria
Bayer219 enrolled154 locationsNCT05196035
Recruiting
Phase 1

MR-Guided Radiotherapy Dose Escalation Trial for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma (ESCC)Esophageal Cancer, Squamous Cell
UMC Utrecht30 enrolled1 locationNCT07359417
Recruiting
Not Applicable

Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm

Bladder CancerMuscle Invasive Bladder Cancer
Radboud University Medical Center360 enrolled19 locationsNCT05779631
Recruiting
Phase 3

Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.

Oropharyngeal Squamous Cell CarcinomaLaryngeal Squamous Cell CarcinomaHypopharynx Squamous Cell Carcinoma
Radboud University Medical Center242 enrolled9 locationsNCT05333523
Recruiting
Not Applicable

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Ovarian CancerBRCA1 Gene MutationBRCA2 Gene Mutation+3 more
University Medical Center Nijmegen3,000 enrolled48 locationsNCT04294927
Recruiting
Phase 2

Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab

NeoplasmsNeoplasms by SiteUrinary Bladder Neoplasm+8 more
The Netherlands Cancer Institute90 enrolled9 locationsNCT06237920
Recruiting
Phase 3

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Leukemia, Acute Lymphoblastic
Mats Heyman6,430 enrolled130 locationsNCT04307576
Recruiting

SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)

Chronic Spontaneous Urticaria (CSU)Hidradenitis Suppurativa (HS)Psoriasis (PsO)+2 more
Leiden University Medical Center840 enrolled8 locationsNCT07021495
Recruiting

Prospective Bladder Cancer Infrastructure (ProBCI)

Bladder Cancer
Prospective Bladder Cancer Infrastructure Foundation3,600 enrolled23 locationsNCT04503577
Recruiting
Not Applicable

Stereotactic Body Radiation Therapy After Chemotherapy for Unresectable Perihilar Cholangiocarcinoma

Klatskin Tumor
Erasmus Medical Center30 enrolled8 locationsNCT06493734