University Medical Center Utrecht

Utrecht, Netherlands

28 recruiting

Showing 120 of 73 trials

Recruiting
Phase 4

Safety and Efficacy of Intravenous Thrombolysis in Patients With Ischemic Stroke and Direct Oral Anticoagulants Intake

Ischemic Stroke
Insel Gruppe AG, University Hospital Bern906 enrolled14 locationsNCT06571149
Recruiting
Phase 2

Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders

Immune Thrombocytopenia
Incyte Corporation56 enrolled40 locationsNCT07104565
Recruiting
Phase 3

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Non-small Cell Lung CancerAnaplastic Lymphoma Kinase-positive
Nuvalent Inc.450 enrolled157 locationsNCT06765109
Recruiting
Phase 3

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled6 locationsNCT06888817
Recruiting
Phase 1

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Diffuse Large B-Cell Lymphoma (DLBCL)Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)+6 more
Nurix Therapeutics, Inc.572 enrolled62 locationsNCT05131022
Recruiting
Phase 1Phase 2

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

Non-small Cell Lung Cancer (NSCLC)KRAS, NRAS, HRAS-mutated NSCLCKRAS G12C-mutated Solid Tumors, Lung Cancer+2 more
Revolution Medicines, Inc.616 enrolled93 locationsNCT06162221
Recruiting
Phase 3

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuriaChildren
Bayer100 enrolled179 locationsNCT05457283
Recruiting
Not Applicable

EMR Versus ESD for Barrett's Neoplasia

Esophageal CancerBarretts Esophagus With DysplasiaBarrett Adenocarcinoma
St. Antonius Hospital331 enrolled6 locationsNCT05276791
Recruiting
Phase 2

A Study of Pegcetacoplan in Pediatric Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria, PNHParoxysmal Hemoglobinuria
Apellis Pharmaceuticals, Inc.12 enrolled12 locationsNCT04901936
Recruiting
Phase 3

Cannabidiol as add-on Therapy for Children With Refractory Epilepsy (CBD-uN1que), a High-quality Individualized Approach: a Series of N-of-1 Trials

Refractory EpilepsyEpilepsyRefractory Epilepsy in Children
UMC Utrecht50 enrolled1 locationNCT07668856
Recruiting
Phase 3

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuria
Bayer219 enrolled164 locationsNCT05196035
Recruiting
Not Applicable

Radiation Free Study

Aortic Aneurysm
Philips Clinical & Medical Affairs Global182 enrolled11 locationsNCT06549348
Recruiting
Not Applicable

Innovative Brain-Computer Interface for People With Spinal Cord Injury

QuadriplegiaSpinal Cord InjuryTetraplegia C1-C4
UMC Utrecht1 enrolled1 locationNCT07640711
Recruiting
Not Applicable

Evaluating How a Tinnitus Implant Affects Tinnitus Loudness in Adults With Chronic Tinnitus and Varying Levels of Hearing Loss

TinnitusNormal HearingHearing Loss, Bilateral or Unilateral
Cochlear16 enrolled2 locationsNCT06641999
Recruiting
Not Applicable

Self-Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD) (SERRA-I Study)

Coronary microvascular diseaseCoronary Microvascular Dysfunction
VahatiCor, Inc.30 enrolled3 locationsNCT06991322
Recruiting
Not Applicable

FAPI Molecular Imaging for Diagnosis of the CMS4 Unfavorable Colorectal Cancer Subtype

Metastatic Colorectal CancerMetastatic Cancer to Liver
UMC Utrecht45 enrolled1 locationNCT06191120
Recruiting
Not Applicable

Personalized Live-remote Exercise Training for Cancer Survivors

Neoplasms
UMC Utrecht350 enrolled1 locationNCT06270628
Recruiting
Not Applicable

Randomized Trial on Same-day SBRT and Surgical Stabilization for Symptomatic Spinal Metastases

Spinal Metastases
UMC Utrecht100 enrolled1 locationNCT05575323
Recruiting
Phase 4

Staphylococcus Aureus Network Adaptive Platform Trial

Staphylococcus Aureus Bacteremia
University of Melbourne8,000 enrolled161 locationsNCT05137119
Recruiting
Phase 3

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Leukemia, Acute Lymphoblastic
Mats Heyman6,430 enrolled138 locationsNCT04307576