Clinical Trials in Bethesda, Maryland
12 recruiting
Showing 1–20 of 77 trials
Recruiting
Phase 2
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Stage IV Renal Cell Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8Large Cell Neuroendocrine Carcinoma+42 more
National Cancer Institute (NCI)314 enrolled576 locationsNCT03866382
Recruiting
Phase 3
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
Stage IIIB Lung Cancer AJCC v8Stage IV Lung Cancer AJCC v8Advanced Lung Non-Squamous Non-Small Cell Carcinoma+2 more
National Cancer Institute (NCI)300 enrolled604 locationsNCT04181060
Recruiting
Phase 2
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Malignant Female Reproductive System Neoplasm+12 more
National Cancer Institute (NCI)2,900 enrolled475 locationsNCT05564377
Recruiting
Phase 1
Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma+37 more
National Cancer Institute (NCI)51 enrolled23 locationsNCT04704661
Recruiting
Phase 2
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
Endocrine Tumors
National Cancer Institute (NCI)285 enrolled1 locationNCT03412877
Recruiting
Phase 2
Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)
Small Cell Carcinoma of the BladderHigh Grade Neuroendocrine Tumors of the Urinary Tract
National Cancer Institute (NCI)45 enrolled1 locationNCT06228066
Recruiting
Phase 2
Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma+28 more
National Cancer Institute (NCI)36 enrolled4 locationsNCT04550494
Recruiting
Phase 1
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
Advanced Breast CancerAdvanced Solid TumorsMetastatic Pancreatic Cancer+3 more
National Cancer Institute (NCI)116 enrolled2 locationsNCT04222413
Recruiting
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
Stomach NeoplasmsMesotheliomaPancreatic Neoplasms+2 more
National Cancer Institute (NCI)1,000 enrolled1 locationNCT01950572
Recruiting
Phase 3
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
Zai Lab (Shanghai) Co., Ltd.480 enrolled14 locationsNCT07218146
Recruiting
Phase 3
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Non-small Cell Carcinoma
Pfizer680 enrolled253 locationsNCT07144280
Recruiting
Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols
Multiple MyelomaLymphoma, Non-HodgkinLeukemia-Lymphoma, Adult T-Cell+1 more
National Cancer Institute (NCI)500 enrolled1 locationNCT02682667
Recruiting
Rapid Autopsy and Procurement of Cancer Tissue
Lung CancersMesotheliomaThymus Tumors+2 more
National Cancer Institute (NCI)275 enrolled1 locationNCT01851395
Recruiting
Evaluation for NCI Surgery Branch Clinical Research Protocols
MelanomaSynovial Cell Cancer
National Cancer Institute (NCI)7,000 enrolled1 locationNCT00001823
Recruiting
Phase 1Phase 2
A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors
Advanced Solid TumorsSCLCHRD Cancer
National Cancer Institute (NCI)120 enrolled1 locationNCT04826341
Recruiting
Phase 1
A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing
Locally Advanced Alveolar Soft Part SarcomaMetastatic Alveolar Soft Part Sarcoma
National Cancer Institute (NCI)30 enrolled1 locationNCT06066138
Recruiting
Phase 3
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
Prostate Cancer
AstraZeneca700 enrolled328 locationsNCT06952803
Recruiting
Collection of Blood From Patients With Cancer
Breast CancerLiver CancerProstate Cancer+2 more
National Cancer Institute (NCI)1,750 enrolled1 locationNCT00034216
Recruiting
Genomic Services Research Program
Breast CancerColon Cancer
National Human Genome Research Institute (NHGRI)5,000 enrolled1 locationNCT02595957
Recruiting
Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy
Prostate CancerProstatic Neoplasms
National Cancer Institute (NCI)300 enrolled1 locationNCT01834001