Clinical Trials in Cardiff, Wales

18 recruiting

Showing 118 of 18 trials

Recruiting
Phase 3

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

Cardiovascular Disease and Lipoprotein(a)
Novartis Pharmaceuticals5,700 enrolled492 locationsNCT07517263
Recruiting
Phase 2

Methods of T Cell Depletion Trial (MoTD)

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaHodgkin Lymphoma+6 more
University of Birmingham400 enrolled17 locationsNCT04888741
Recruiting
Phase 2Phase 3

(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

Indolent Systemic MastocytosisSmoldering Systemic Mastocytosis
Blueprint Medicines Corporation534 enrolled64 locationsNCT04910685
Recruiting
Phase 3

A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

HER2 MutationAdvanced Non-Small Cell Lung Cancer
Bayer444 enrolled283 locationsNCT06452277
Recruiting

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

Pulmonary Embolism
Penumbra Inc.1,500 enrolled74 locationsNCT04798261
Recruiting
Phase 2

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

Breast Cancer Metastatic
ALX Oncology Inc.120 enrolled32 locationsNCT07007559
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Lung CancerEGFRNSCLC, Stage IB-IIIA+5 more
Taiho Oncology, Inc.360 enrolled253 locationsNCT07128199
Recruiting
Phase 1Phase 2

A Study of ATTR-01 in Participants With Select Epithelial Solid Tumours

Solid Tumor, Adult
Accession Therapeutics Limited72 enrolled7 locationsNCT06977737
Recruiting
Phase 3

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.160 enrolled138 locationsNCT05667142
Recruiting
Not Applicable

RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

Heart Failure
University Hospital Southampton NHS Foundation Trust2,504 enrolled47 locationsNCT05568069
Recruiting
Phase 3

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

Extensive-stage Small-cell Lung Cancer
BioNTech SE621 enrolled138 locationsNCT06712355
Recruiting

Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

Intubation ComplicationFailed or Difficult Intubation, SequelaIntubation; Difficult
Children's Hospital of Philadelphia150,000 enrolled87 locationsNCT02493478
Recruiting
Phase 1

Investigating Idetrexed and Olaparib in Patients With Ovarian Cancer

High Grade Serous Ovarian Cancer
Institute of Cancer Research, United Kingdom33 enrolled3 locationsNCT06976892
Recruiting
Phase 2

PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study of DNA Damage Response Inhibition With or Without Anti-PD-L1 Immunotherapy in Patients With Neoadjuvant Treatment Resistant Residual Triple Negative Breast Cancer

Breast NeoplasmTriple Negative Breast Cancer(TNBC)HRD
Institute of Cancer Research, United Kingdom119 enrolled6 locationsNCT03740893
Recruiting
Not Applicable

HeEL Pain Pathways Feasibility Study

Plantar fasciitis
Cardiff and Vale University Health Board50 enrolled1 locationNCT06967168
Recruiting

Are We Providing Timely Access to Musculoskeletal Outpatient Therapy Services? an Exploratory Study

Musculoskeletal
Cardiff and Vale University Health Board135 enrolled1 locationNCT06829875
Recruiting
Phase 3

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Community-acquired Pneumonia, Influenza, COVID-19
UMC Utrecht20,000 enrolled408 locationsNCT02735707
Recruiting
Phase 2

Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Suppression

Metastatic Breast CancerAdvanced Breast CancerER+ Breast Cancer
Royal Marsden NHS Foundation Trust324 enrolled18 locationsNCT04920708