Clinical Trials in East London, South Africa
12 recruiting
Showing 1–18 of 18 trials
Recruiting
Phase 2Phase 3
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
Breast Neoplasms
Bristol-Myers Squibb500 enrolled295 locationsNCT06926868
Recruiting
Phase 2
Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary Tuberculosis
Drug Susceptible Pulmonary Tuberculosis
Gates Medical Research Institute150 enrolled13 locationsNCT07525427
Recruiting
Phase 3
A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza
Influenza
Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)7,500 enrolled181 locationsNCT07159763
Recruiting
Phase 3
A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)
Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,580 enrolled30 locationsNCT07071623
Recruiting
Phase 3
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Crohn's Disease
Sanofi980 enrolled259 locationsNCT07184931
Recruiting
Phase 3
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Heart Failure
AstraZeneca11,300 enrolled942 locationsNCT06677060
Recruiting
Phase 3
A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis
Pulmonary Tuberculosis
Otsuka Pharmaceutical Development & Commercialization, Inc.532 enrolled35 locationsNCT07209761
Recruiting
Not Applicable
Therapeutic Drug Monitoring for Linezolid in the Treatment of Rifampin-resistant Tuberculosis
Drug Resistant TuberculosisRifampin-resistant Tuberculosis
Albert Einstein College of Medicine280 enrolled1 locationNCT06590428
Recruiting
Phase 3
A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
Ischemic Stroke; Ischemic Attack, Transient
Janssen Research & Development, LLC15,000 enrolled880 locationsNCT05702034
Recruiting
Performance, Acceptability, and Usability of a Novel Rapid Lateral Flow Test for Detecting Neisseria Gonorrhoeae in Pregnant and Symptomatic Women Attending Clinics in South Africa.
Neisseria Gonorrheae Infection
Foundation for Professional Development (Pty) Ltd1,239 enrolled1 locationNCT07530406
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living in a TB Endemic Region.
Tuberculosis (TB)
International AIDS Vaccine Initiative5,500 enrolled16 locationsNCT06272812
Recruiting
Phase 2Phase 3
Study of Bictegravir/Lenacapavir in Children and Adolescents With HIV-1
HIV-1-infection
Gilead Sciences75 enrolled21 locationsNCT06532656
Recruiting
Not Applicable
Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB Treatment
Drug Resistant Tuberculosis
Johns Hopkins University2,944 enrolled5 locationsNCT05671718
Recruiting
Phase 2Phase 3
A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children
BioNTech SE4,292 enrolled134 locationsNCT05543616
Recruiting
Not Applicable
Assessing the Feasibility of Coach Mpilo for Men With TB and HIV
TuberculosisHIV
Arizona State University240 enrolled1 locationNCT07117370
Recruiting
Not Applicable
Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING PUMA)
ART Adherence
University of California, San Francisco500 enrolled1 locationNCT06423612
Recruiting
Not Applicable
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
HIV InfectionsTreatment AdherenceMen
Desmond Tutu HIV Foundation3,642 enrolled2 locationsNCT05602376
Recruiting
Not Applicable
Tailoring Healthy Relationships to Improve HIV Outcomes
HIV
Arizona State University120 enrolled1 locationNCT05708261