Clinical Trials in Valencia, California

22 recruiting

Showing 120 of 21 trials

Recruiting
Phase 3

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

Chronic Obstructive Pulmonary Disease
Sanofi942 enrolled183 locationsNCT07190209
Recruiting
Phase 3

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Prostate CancerCancer of the ProstateHormone Sensitive Prostate Cancer+1 more
Pfizer1,000 enrolled300 locationsNCT07028853
Recruiting
Phase 1Phase 2

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

Staphylococcus Aureus
AstraZeneca231 enrolled42 locationsNCT06749457
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Crohn's Disease
Merck Sharp & Dohme LLC1,200 enrolled499 locationsNCT06430801
Recruiting
Phase 2

Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

Diabetic Kidney Disease (DKD)
Regeneron Pharmaceuticals270 enrolled47 locationsNCT07271186
Recruiting
Phase 3

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease
Sanofi980 enrolled196 locationsNCT07184931
Recruiting
Phase 3

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis
Sanofi980 enrolled191 locationsNCT07184996
Recruiting
Phase 2

Rademikibart Add-on Treatment of an Acute Asthma Exacerbation (Seabreeze STAT Asthma)

Asthma Acute
Connect Biopharm LLC160 enrolled52 locationsNCT06940141
Recruiting
Phase 2

Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)

COPD Acute Exacerbation
Connect Biopharm LLC160 enrolled51 locationsNCT06940154
Recruiting
Phase 2

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

Urothelial Carcinoma
Seagen, a wholly owned subsidiary of Pfizer372 enrolled223 locationsNCT04879329
Recruiting
Phase 3

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

Immunoglobulin A NephropathyIgAN
Alexion Pharmaceuticals, Inc.510 enrolled267 locationsNCT06291376
Recruiting
Phase 2

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

Chronic Kidney Disease
Boehringer Ingelheim416 enrolled156 locationsNCT06926660
Recruiting
Not Applicable

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

Metabolic SyndromeDiabetes Mellitus, Type 2Prediabetes
Cleerly, Inc.7,500 enrolled123 locationsNCT06112418
Recruiting

A DirEct to PatieNt Study in Chronic Pain

Chronic Pain
Boston Scientific Corporation50,000 enrolled1 locationNCT05515341
Recruiting
Phase 3

Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

Chronic Kidney DiseasesType 2 Diabetes Mellitus
Prokidney685 enrolled95 locationsNCT05099770
Recruiting
Phase 2

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

HypertensionUncontrolled Hypertension
Vanda Pharmaceuticals240 enrolled28 locationsNCT07090161
Recruiting
Phase 2

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis
Gilead Sciences176 enrolled129 locationsNCT06029972
Recruiting
Phase 1

R-3750 in Patients With Mild to Moderate Ulcerative Colitis

Ulcerative ColitisUlcerative Colitis ChronicUlcerative Colitis Chronic Mild+1 more
Rise Therapeutics LLC36 enrolled4 locationsNCT05666960
Recruiting
Phase 2

Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

APOL1-mediated Kidney Disease
AstraZeneca96 enrolled77 locationsNCT06824987
Recruiting
Phase 2

To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

Difficult to Control Hypertension
E-Star BioTech, LLC120 enrolled29 locationsNCT06343298