CompletedPhase 4ACTRN12605000034639

Does a single oral dose of dexamethasone after successful emergency department treatment of migraine reduce the incidence or severity of rebound headache within 48 hours?

Sponsor

The Joseph Epstein Centre for Emergency Medicine Research

Enrollment

76 participants

Start Date

Jan 4, 2005

Study Type

Interventional

Conditions

Migraine

Eligibility

Sex: Both males and femalesMin Age: 17 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests whether a single dose of dexamethasone (a steroid) given after successful emergency treatment of a migraine can reduce the chance of the headache coming back within 48 hours. Adults aged 17 and older diagnosed with migraine in the emergency department may be eligible.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

The primary aim is to compare the proportion of patients who experience rebound headache within 48 hours after ED treatment of migraine between a group treated with single dose oral dexamethasone 8mg

The primary aim is to compare the proportion of patients who experience rebound headache within 48 hours after ED treatment of migraine between a group treated with single dose oral dexamethasone 8mg and a group treated with placebo.Secondary aims are to compare headache severity, analgesia/ health service use, adverse events and return to normal functioning between the groups.