The effect of Glycine Betaine on fasting and Post methionine load homocysteine concentrations in healthy volunteers.

This study looks at whether a supplement called glycine betaine (also known as betaine) can lower levels of homocysteine in the blood. Homocysteine is a chemical that, when present at high levels, is linked to heart disease and stroke. Researchers are testing this in healthy volunteers to see how betaine affects homocysteine both when fasting and after taking an amino acid called methionine. You may be eligible if: - You are 18 years or older - You are generally healthy with no history of heart or blood vessel disease - You are not currently taking any medications for an illness - You have a normal haemoglobin (red blood cell) level You may NOT be eligible if: - You have low levels of vitamin B12, vitamin B6, or folate - You carry a specific gene variant called the 677C>T polymorphism in the MTHFR gene Talk to your doctor about whether this trial might be right for you.