RecruitingACTRN12605000504617

beta blockers and lung function in heart failure

Comparison of non-selective and beta1-selective beta-blockers on respiratory and arterial function and cardiac chamber dynamics in patients with chronic stable congestive cardiac failure


Sponsor

Chris Hayward

Enrollment

40 participants

Start Date

Jul 1, 2005

Study Type

Interventional

Conditions

Summary

This study will compare 3 beta blocker tablets routinely used in treating patients with heart failure. There are theoretical reasons for differences between the tablets (particularly with respect to lung function and blood pressure changes), although this has not been tested in head-to-head comparison.


Eligibility

Sex: Both males and females

Plain Language Summary

Simplified for easier understanding

This study compares three different beta-blocker medications — a class of drugs commonly used to treat heart failure — to see how they affect lung function and blood pressure. While all three are used for heart failure, there are reasons to think they may work differently, especially for patients who also have breathing problems such as asthma or chronic lung disease. The study will compare the effects of these medications head-to-head in stable heart failure patients. You may be eligible if: - You have stable heart failure (classified as NYHA Class I, II, or III) - You are already taking a beta-blocker medication - You may have breathing/airway problems (this is specifically included in half the study group) You may NOT be eligible if: - There are no specific exclusion criteria listed for this study Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Comparison of three clinically available beta-blockers (carvedilol, metoprolol succinate, bisoprolol) in cardiac failure.

Comparison of three clinically available beta-blockers (carvedilol, metoprolol succinate, bisoprolol) in cardiac failure.


Locations(1)

Australia

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ACTRN12605000504617


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