RecruitingACTRN12605000504617

beta blockers and lung function in heart failure

Comparison of non-selective and beta1-selective beta-blockers on respiratory and arterial function and cardiac chamber dynamics in patients with chronic stable congestive cardiac failure


Sponsor

Chris Hayward

Enrollment

40 participants

Start Date

Jul 1, 2005

Study Type

Interventional

Conditions

Summary

This study will compare 3 beta blocker tablets routinely used in treating patients with heart failure. There are theoretical reasons for differences between the tablets (particularly with respect to lung function and blood pressure changes), although this has not been tested in head-to-head comparison.


Eligibility

Sex: Both males and females

Inclusion Criteria1

  • Stable NYHA Class I, II, III CCF pts already receiving beta-blocker therapy. Half of study population to have defined (on basis of RFT testing) or treated airways disease.

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Interventions

Comparison of three clinically available beta-blockers (carvedilol, metoprolol succinate, bisoprolol) in cardiac failure.

Comparison of three clinically available beta-blockers (carvedilol, metoprolol succinate, bisoprolol) in cardiac failure.


Locations(1)

Australia

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ACTRN12605000504617


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