2006 Cholesterol challenge Study
Comprehensive Lifestyle Intervention Program (CLIP) compared to Statin Therapy plus standard lifestyle advice in managing lipids and CVD risk in individuals with hypercholesterolaemia
CSIRO Human Nutrition
150 participants
Mar 27, 2006
Interventional
Conditions
Summary
Aim: To test the efficacy of a strucured diet and lifestyle program for plasma cholesterol and weight reduction which can be used at point of care to reduce absolute cardiovascular risk and the need for lipid lowering drugs.
Eligibility
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Interventions
The primary objective in this study is to develop a 6 week comprehensive diet and lifestyle intervention program (CLIP) targeted to achieve a cholesterol reduction comparable to a statin (S) and to compare this approach to standard lifestyle advice with (S+L) and without (L) statin therapy on plasma lipids and cardiovascular risk factors. Group 1 CLIP Program (low saturated fat + sterols + soluble fibre + weight reduction + exercise).
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ACTRN12606000127505