Hypercholesterolaemia Clinical Trials

15 recruiting

Frequently Asked Questions

Common questions about Hypercholesterolaemia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting
Phase 1

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

HypercholesterolaemiaMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG90 enrolled18 locationsNCT07491172
Recruiting

Evaluation of Adherence, Persistence and Efficacy of Treatment With Alirocumab 300mg in Italy

Hypercholesterolaemia
Federico II University1,500 enrolled1 locationNCT07375225
Recruiting
Not Applicable

An Efficacy and Safety Study of Akkermansia Muciniphila AKM Lab-01 in Hypercholesterolaemia

Hypercholesterolaemia
Moon (Guangzhou) Biotechnology Co., Ltd.60 enrolled1 locationNCT06974266
Recruiting
Phase 4

LATAM LOWERS LDL-C

Hypercholesterolaemia
Novartis Pharmaceuticals520 enrolled11 locationsNCT06501443
Recruiting
Not Applicable

Computerized Decision Support for Identification and Management of Familial Hypercholesterolemia

Familial Hypercholesterolaemia
Brigham and Women's Hospital450 enrolled1 locationNCT06743659
Recruiting

Cardiovascular Risk in Children With Chronic Conditions Study

Obesity and OverweightLymphomaLeukemia+13 more
Semmelweis University300 enrolled3 locationsNCT07086989
Recruiting
Phase 1

A Study to Compare PK Characteristics and Safety Profiles Between AD-228B and AD-2284

Primary Hypercholesterolaemia
Addpharma Inc.60 enrolled1 locationNCT06884098
Recruiting

The Spanish Familial Hypercholesterolaemia Cohort Study

Familial Hypercholesterolaemia
Fundación Hipercolesterolemia Familiar4,141 enrolled1 locationNCT02693548
Recruiting
Phase 3

efficacy of LOw dose antihypertensive and lipid lowering pill combinations To improve stroke oUtcomeS (LOTUS)

HypercholesterolaemiaHypertensionTransient Ischaemic Attack+1 more
The George Institute for Global Health Australia400 enrolled14 locationsACTRN12624001279516
Recruiting
Phase 3

Efficacy and Safety of JS002 as Monotherapy in Patients With Primary Hypercholesterolaemia and Mixed Dyslipidemia

Primary Hypercholesterolaemia and Mixed Dyslipidemia
Shanghai Junshi Bioscience Co., Ltd.582 enrolled1 locationNCT05621070
Recruiting
Phase 1

Effect of Fucoidan on glucose control and markers of cardiometabolic health after chronic dosing

Insulin Resistance/sensitivityHypercholesterolaemiaObesity+3 more
University of Tasmania.80 enrolled1 locationACTRN12614000495628
Recruiting
Phase 4

Rosuvastatin versus Protease Inhibitor Switching for Hypercholesterolaemia in HIV-infected Adults.

Hypercholesterolaemia associated with ritonavir-boosted protease inhibitor therapy in of HIV-infected adults
St. Vincent's Hospital, Sydney60 enrolled1 locationACTRN12612000732886
Recruiting
Phase 4

VYTUL

Hypercholesterolaemia
Merck Sharp & Dohme Australia & Schering-Plough Pty. Limited550 enrolled1 locationACTRN12606000374561
Recruiting
Phase 4

Effect of barley foods on cardiovascular health biomarkers

Hypercholesterolaemia
Commonwealth Scientific Industrial Research Organisation, Human Nutrition30 enrolled1 locationACTRN12606000355572
Recruiting
Phase 4

2006 Cholesterol challenge Study

Hypercholesterolaemia
CSIRO Human Nutrition150 enrolled1 locationACTRN12606000127505
Recruiting

Coenzyme Q10 and tolerability of simvastatin in subjects with a history of statin-induced myalgia

Statin-induced myalgia in subjects with hypercholesterolaemia
Lipid and Diabetes Research Group, Christchurch Hospital44 enrolled1 locationACTRN12605000545662