Not Yet RecruitingPhase 4ACTRN12606000289516

Pulmonary Artery Remodelling With Bosentan

Open Label, Non Comparative Study to Investigate the Effect of Bosentan on Pulmonary Artery Remodelling in Pulmonary Arterial Hypertension (PAH)

Sponsor

Actelion Phrmaceuticals Australia

Enrollment

15 participants

Start Date

Jul 31, 2006

Study Type

Interventional

Conditions

Hypertension, Pulmonary

Summary

The main purpose of this study is to investigate whether bosentan (Tracleer®) affects the wall thickness of the pulmonary arteries in patients with idiopathic pulmonary arterial hypertension (iPAH) and PAH related to systemic sclerosis (PAH-SSc)

Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study investigates Pulmonary Artery Remodelling With Bosentan. It is looking for both men and women, aged 18 and older who have symptomatic (modified New York Heart Associate (NYHA) class III) iPAH or PAH-SScPAH confirmed by right heart catheterisation performed within 3 mon.... People who are pregnant or breastfeeding individuals cannot take part. If you are interested, you may need to attend study visits and follow the research team's instructions.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Bosentan be orally administered at 62.5mg bid for 4 weeks, followed by a target dose of 125mg bid for 6 months

Locations(1)

Australia

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