RecruitingACTRN12606000363583

The use of Temgesic in combination with exposure therapy to treat social anxiety symptoms.

A randomised controlled trial to evaluate the effect of Temgesic (0.2mg) in combination with exposure therapy for the treatment of social phobia to improve the severity of social phobia symptoms.


Sponsor

University of New South Wales

Enrollment

50 participants

Start Date

Aug 23, 2006

Study Type

Interventional

Conditions

Summary

This study tests whether Temgesic improves the effectiveness of exposure therapy for decreasing social anxiety symptoms. We predict that individuals from the community diagnosed with social phobia who receive four exposure therapy sessions in combination with Temgesic will experience a greater reduction in social anxiety symptoms in comparison to individuals who received the placebo in combination with four exposure therapy sessions. Participants receive, in total, five weekly group therapy sessions, the first is educational and the next four consist of public speaking exposure therapy. One month post intervention participants are assessed for social anxiety symptoms as well as other general health indicators. All subjects, therapists, assessors, and data entry staff are blind to condition.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study is testing whether a medication called Temgesic (buprenorphine, a low-dose pain and anxiety reliever) can improve the results of exposure therapy for social anxiety. Social phobia causes intense fear and avoidance of social situations such as speaking in public, meeting new people, or being watched by others. Participants will attend five weekly group therapy sessions and take either Temgesic or a placebo before public speaking exercises. One month after the program ends, their anxiety levels will be measured to see if Temgesic helped them overcome their fear more effectively. You may be eligible if: - You are an adult (18 years or older) - Your primary (main) diagnosis is social phobia (social anxiety disorder) You may NOT be eligible if: - You have significant liver or kidney problems - You have impaired breathing or a breathing condition - You have had a head injury - You have a substance abuse or dependence problem Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Participants with social phobia are given group exposure based therapy over 5 weekly treatment sessions in combination with a sublingual dose of Temgesic (0.2mg) or placebo.

Participants with social phobia are given group exposure based therapy over 5 weekly treatment sessions in combination with a sublingual dose of Temgesic (0.2mg) or placebo. Exposure therapy consists of 3 to 10 minute speech tasks in front of a group where a decrease in anxiety within this situation is observed.


Locations(1)

Australia

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ACTRN12606000363583


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