A structural and functional imaging research of children with Attention Deficit Hyperactivity Disorder (ADHD)
Structural and functional imaging maps of children with Attention Deficit Hyperactivity Disorder (ADHD) using Magnetic Resonance Imaging (MRI) scan of the brain and methylphenidate (MPH)
Children Psychiatry Department, Institute of Mental Health, Peking University
30 participants
Aug 21, 2007
Interventional
Conditions
Eligibility
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Interventions
All participants will be scanned by a MRI scanner. The total time of a scan session is about 45 minutes and data of structural and functional images of the subjects’ brains will be collected. In the functional part, the subjects will perform a cognitive task. Children with ADHD will be scanned twice. About 1 hour before one of the scan sessions, the patients will take a single dose (10 mg) of MPH orally, which is a drug commonly used in the treatment of ADHD. Then the patients will be scanned. (About 1 hour before the other scan session, the patients will take the placebo, which is described in the “Comparator / control treatment” part of the form.) The order of the two sessions will be counterbalanced across the patients. The interval between the two sessions will be about 1 week, which is thought to be enough for the clearance of the drug.
Locations(1)
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ACTRN12608000059369