An Open-Label, Multi-Center, Randomized Study Evaluating the Safety and Efficacy of Flutcasone Propionate Nasal Drops, Nasal Spray and Suspension for Nebulization via Nasal Inhalation in Post-Surgical Subjects with Chronic Sinusitis

This study is comparing three different ways of delivering a steroid nasal spray called fluticasone propionate to people who have had sinus surgery and still have ongoing chronic sinusitis (long-term inflammation of the sinuses). The three methods are: nose drops, a nasal spray, and a nebuliser (a device that turns liquid into a fine mist inhaled through the nose). All three deliver the same medication — researchers want to know which delivery method works best at reducing sinus symptoms like congestion, post-nasal drip, and facial pressure. You may be eligible if: - You are 18 years of age or older - You have had sinus surgery - You have ongoing symptoms of chronic sinusitis, including nasal congestion and post-nasal drip You may NOT be eligible if: - You are pregnant, breastfeeding, or of childbearing potential without adequate contraception - You have a known allergy to fluticasone propionate - You have an active sinus infection with purulent (infected) discharge - You have used antibiotics, nasal steroids, or oral steroids recently before the study - You have a condition that requires ongoing steroid therapy Talk to your doctor about whether this trial might be right for you.