CompletedPhase 2ACTRN12609000124235

Dietary Oils in Stress Pilot Study

A Pilot Randomised Controlled Double Blind Intervention Study of the Effects of docosahexaenoic acid-(DHA)-Rich Fish Oil Compared with Olive Oil in Psychological Stress.


Sponsor

Blackmores Ltd

Enrollment

40 participants

Start Date

Aug 13, 2008

Study Type

Interventional

Conditions

Summary

The aim of the study is to demonstrate a protective role of omega 3 fatty acids during time of intense psychological stress (exam stress in university students) compared with a placebo.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 45 Yearss

Inclusion Criteria1

  • Fulltime students, aged between 18-45, has normal eating habits, has not radically changed diet in past 3m, consumes less than 2 fish meals per week on average, describes self as someone that experiences a lot of stress under pressure, willing to refrain from other medications during trial

Exclusion Criteria1

  • allergy to seafood, aversion to taking fish oil, has taken a course of fish oil in past 3m, has a systemic chronic disease such as diabetes or heart disease, has a history of haemophilia or any type of clotting disorder, has a history of psychiatric illness, history of taking antipsychotics or antidepressants, current infectious, allergic or inflammatory response, any medications in past 2 weeks, non-sterioidal antiinflammatory medications in past 30 days, corticosteroids in past 3m, females with menstrual irregularities, females that are pregnant or lactating, poor venous access, any other condition which in the opinion of the investigators may impact on study outcomes.

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Interventions

DHA-rich Fish Oil Supplements, 4 capsules per day for 12 weeks. Each capsule contains 1000mg fish oil, containing (DHA) 500mg, and eicosapentaenoic acid (EPA) 100 mg

DHA-rich Fish Oil Supplements, 4 capsules per day for 12 weeks. Each capsule contains 1000mg fish oil, containing (DHA) 500mg, and eicosapentaenoic acid (EPA) 100 mg


Locations(1)

Australia

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ACTRN12609000124235


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