A prospective, single-masked, cross-over, randomised clinical trial assessing ocular comfort and ocular changes with and without lens replacement during the day with AIR OPTIX (trademark) AQUA contact lenses worn by experienced wearers over three days

This is a prospective, single-masked, cross-over, randomised clinical trial, with participants wearing AIR OPTIX AQUA contact lenses bilaterally over 3 days following initial lens dispense. Participants will initially be fitted with contact lenses . This is followed by three days of wear with the same lens type. Each day corresponds to one stage of the study. For two of the stages, participants will insert their own study lenses and these will be removed after approximately five hours of wear. Either the same lenses will be re-inserted after a brief soak in saline or a new pair of lenses will be inserted. For the other stage, participants will insert their own study lenses and wear the same lenses for the day without removal. The order in which this occurs will be randomised for all stages and masked when lenses are removed during the day. Subjective responses will also be evaluated at regular intervals during each stage. It is expected that most participants will have six scheduled visits, comprising the baseline visit followed by two stages with two visits per stage and one stage with one visit. * Baseline visit * Stages where lenses removed during the day o Visit 1 o Visit 2 * Stage where lenses not removed during the day: o Visit 1 * Take home questionnaires (THQ) at regular intervals during the day for all stages