Not Yet RecruitingPhase 3Phase 4ACTRN12609000443291

Efficacy and Safety Comparison of two different topical gels (one active and one vehicle) in combination with an oral antibiotic in the treatment of Moderate to Severe Acne Vulgaris.

Efficacy and Safety Comparison of Adapalene 0.1%/Benzoyl Peroxide 2.5% gel associated with Lymecycline 300mg Capsules versus Adapalene 0.1%/Benzoyl Peroxide 2.5% Vehicle Gel associated with Lymecycline 300mg Capsules in the treatment of Moderate to Severe Acne Vulgaris.


Sponsor

Galderma Australia Pty Ltd

Enrollment

360 participants

Start Date

Aug 1, 2009

Study Type

Interventional

Conditions

Summary

In an attempt to further improve the management of moderate to severe acne, this study aims to investigate the efficacy and safety of a combination of a topical acne gel and an oral antibiotic.


Eligibility

Sex: Both males and femalesMin Age: 12 YearssMax Age: 35 Yearss

Plain Language Summary

Simplified for easier understanding

This study compares an active topical gel combined with an oral antibiotic against a vehicle gel plus antibiotic for treating moderate to severe acne in people aged 12 to 35. The goal is to determine which treatment clears acne more effectively.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

1g of Adapalene 0.1%/Benzoyl Peroxide 2.5% gel will be applied once daily in the evening to the entire face for 12 weeks. One Lymecycline 300mg Capsule will be taken orally in the morning with an ade

1g of Adapalene 0.1%/Benzoyl Peroxide 2.5% gel will be applied once daily in the evening to the entire face for 12 weeks. One Lymecycline 300mg Capsule will be taken orally in the morning with an adequate amount of fluid for 12 weeks.


Locations(1)

Australia

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ACTRN12609000443291


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