Acne Clinical Trials

51 recruitingLast updated: May 21, 2026

There are 51 actively recruiting acne clinical trials across 18 countries. Studies span Not Applicable, Phase 3, Phase 2, Phase 4, Early Phase 1, Phase 1. Top locations include Brest, France, Melbourne, Victoria, Australia, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Acne Trials at a Glance

51 actively recruiting trials for acne are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Brest, Melbourne, and Houston. Lead sponsors running acne studies include Integrative Skin Science and Research, Nantes University Hospital, and Sanofi Pasteur, a Sanofi Company.

About Acne Clinical Trials

Looking for clinical trials for Acne? There are currently 25 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acne trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acne clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 51 trials

Recruiting
Not Applicable

Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial

Skin healthRosaceaMenopause+5 more
King's College London30 enrolled1 locationNCT07341087
Recruiting
Phase 1Phase 2

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne
Sanofi Pasteur, a Sanofi Company800 enrolled93 locationsNCT06316297
Recruiting
Not Applicable

Subcision With Injection of Poly Deoxyribonucleotide Versus Subcision With Injection of Non-cross Linked Hyaluronic Acid in Rolling Acne Scars Treatment : A Split Face Randomized Controlled Clinical Trial

Rolling Acne Scars
Cairo University20 enrolled1 locationNCT07547956
Recruiting
Phase 4

Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.

Acne vulgaris
Integrative Skin Science and Research30 enrolled1 locationNCT07544251
Recruiting

Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital

Acne
Nantes University Hospital200 enrolled1 locationNCT03465150
Recruiting
Not Applicable

Poly-L-Lactic Acid in Atrophic Acne Scars

Atrophic Acne Scarring
Zagazig University52 enrolled1 locationNCT07523217
Recruiting
Phase 2

Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne

Acne
Shenzhen People's Hospital196 enrolled1 locationNCT07366229
Recruiting
Early Phase 1

Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne Vulgaris

Acne vulgariserythemaPost Inflammtory Erythema
Pham Ngoc Thach University of Medicine60 enrolled1 locationNCT07474883
Recruiting
Phase 2

Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors

ParonychiaAcneiform Eruption Due to ChemicalXerosis Cutis
Hoth Therapeutics, Inc.152 enrolled12 locationsNCT05639933
Recruiting

Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers

Atopic DermatitisHidradenitis SuppurativaAcne+3 more
Innovaderm Research Inc.500 enrolled1 locationNCT05994976
Recruiting
Not Applicable

Evaluation of Juläine (TM) for the Treatment of Atrophic Facial Acne Scars

Acne Scars
Nordberg Medical AB55 enrolled2 locationsNCT07058883
Recruiting
Not Applicable

Reduction of Bacterial Seeding in Total Shoulder Arthroplasty

Prosthetic joint infectionShoulderCutibacterium Acnes+1 more
St. Louis University60 enrolled1 locationNCT07406893
Recruiting
Phase 1

Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne

Acne
Sagimet Biosciences Inc.128 enrolled2 locationsNCT06989840
Recruiting
Not Applicable

The Suitability of Tience® for Treating Acne Scars

AcneAcne Scars
Linio Biotech Oy20 enrolled1 locationNCT07368764
Recruiting
Not Applicable

PRP Plus Fractional CO₂ Laser for Acne Scars

Post-Acne Atrophic ScarsCarbon Dioxide LasersPlatelet-Rich Plasma
Gujranwala medical college District Headquarters Hospital, Gujranwala70 enrolled1 locationNCT07352215
Recruiting
Not Applicable

Cold Atmospheric Plasma for Moderate-to-severe Acne Vulgaris Study

Acne vulgaris
Shenyang Medical College220 enrolled1 locationNCT07056673
Recruiting
Not Applicable

Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars

Acne Scars
University of Nove de Julho84 enrolled1 locationNCT07151599
Recruiting
Phase 3

A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars

Acne Scars
AbbVie395 enrolled10 locationsNCT07207369
Recruiting
Phase 3

A Study to Compare the Efficacy, Safety and Pharmacokinetics of Trifarotene 50 mcg/g Cream in Chinese Subjects With Acne Vulgaris

Acne vulgaris
Galderma R&D561 enrolled1 locationNCT07186413
Recruiting
Phase 1Phase 2

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne

Acne
Sanofi Pasteur, a Sanofi Company120 enrolled4 locationsNCT07013747