Acne Clinical Trials

53 recruitingLast updated: July 25, 2026

There are 53 actively recruiting acne clinical trials across 19 countries. Studies span Not Applicable, Phase 3, Phase 2, Phase 4, Early Phase 1, Phase 1. Top locations include Brest, France, Jacksonville, Florida, United States, Encino, California, United States. Updated daily from ClinicalTrials.gov.


Acne Trials at a Glance

53 actively recruiting trials for acne are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 27 trials, with the heaviest enrollment activity in Brest, Jacksonville, and Encino. Lead sponsors running acne studies include Integrative Skin Science and Research, Nantes University Hospital, and Sanofi Pasteur, a Sanofi Company.

Treatments under study

About Acne Clinical Trials

Looking for clinical trials for Acne? There are currently 25 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acne trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acne clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 53 trials

Recruiting
Phase 1Phase 2

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne

Acne
Sanofi Pasteur, a Sanofi Company228 enrolled4 locationsNCT07013747
Recruiting

Global Healthcare Study on Hidradenitis Suppurativa

Hidradenitis Suppurativa (HS)Hidradenitis Suppurativa (Acne Inversa)
Julia Tatjana Maul9,600 enrolled1 locationNCT07659769
Recruiting
Phase 1

Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne

Acne
Sagimet Biosciences Inc.128 enrolled2 locationsNCT06989840
Recruiting
Phase 3

Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients

Acne vulgaris
Centre Hospitalier Universitaire de Nice420 enrolled19 locationsNCT06447480
Recruiting
Early Phase 1

Weekly Isotretinoin vs Tetracycline for Moderate Acne

Acne vulgaris
Medical University of South Carolina50 enrolled1 locationNCT06225570
Recruiting
Not Applicable

Subcision With Injection of Poly Deoxyribonucleotide Versus Subcision With Injection of Non-cross Linked Hyaluronic Acid in Rolling Acne Scars Treatment.

Atrophic Acne Scars
Cairo University20 enrolled1 locationNCT07547956
Recruiting
Not Applicable

Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial

Skin healthRosaceaMenopause+5 more
King's College London30 enrolled1 locationNCT07341087
Recruiting
Phase 1Phase 2

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne
Sanofi Pasteur, a Sanofi Company800 enrolled93 locationsNCT06316297
Recruiting
Phase 4

Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.

Acne vulgaris
Integrative Skin Science and Research30 enrolled1 locationNCT07544251
Recruiting

Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital

Acne
Nantes University Hospital200 enrolled1 locationNCT03465150
Recruiting
Not Applicable

Poly-L-Lactic Acid in Atrophic Acne Scars

Atrophic Acne Scarring
Zagazig University52 enrolled1 locationNCT07523217
Recruiting
Phase 2

Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne

Acne
Shenzhen People's Hospital196 enrolled1 locationNCT07366229
Recruiting
Early Phase 1

Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne Vulgaris

Acne vulgariserythemaPost Inflammtory Erythema
Pham Ngoc Thach University of Medicine60 enrolled1 locationNCT07474883
Recruiting
Phase 2

Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors

ParonychiaAcneiform Eruption Due to ChemicalXerosis Cutis
Hoth Therapeutics, Inc.152 enrolled12 locationsNCT05639933
Recruiting

Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers

Atopic DermatitisHidradenitis SuppurativaAcne+3 more
Innovaderm Research Inc.500 enrolled1 locationNCT05994976
Recruiting
Not Applicable

Evaluation of Juläine (TM) for the Treatment of Atrophic Facial Acne Scars

Acne Scars
Nordberg Medical AB55 enrolled2 locationsNCT07058883
Recruiting
Not Applicable

Reduction of Bacterial Seeding in Total Shoulder Arthroplasty

Prosthetic joint infectionShoulderCutibacterium Acnes+1 more
St. Louis University60 enrolled1 locationNCT07406893
Recruiting
Not Applicable

The Suitability of Tience® for Treating Acne Scars

AcneAcne Scars
Linio Biotech Oy20 enrolled1 locationNCT07368764
Recruiting
Not Applicable

PRP Plus Fractional CO₂ Laser for Acne Scars

Post-Acne Atrophic ScarsCarbon Dioxide LasersPlatelet-Rich Plasma
Gujranwala medical college District Headquarters Hospital, Gujranwala70 enrolled1 locationNCT07352215
Recruiting
Not Applicable

Cold Atmospheric Plasma for Moderate-to-severe Acne Vulgaris Study

Acne vulgaris
Shenyang Medical College220 enrolled1 locationNCT07056673