Red Cell Life Span (RBC) in Chronic Kidney Disease (CKD)

This study is measuring how long red blood cells survive in people with chronic kidney disease (CKD). Red blood cells normally live about 120 days, but in people with kidney disease they may not last as long. Researchers will track this using a safe radioactive tag applied to the blood cells, and will also look at how this affects a common diabetes test called HbA1c. You may be eligible if: - You are 18 years of age or older - You have moderate CKD (stage III, with a filtration rate of 30–59 mL/min) OR you are on haemodialysis or peritoneal dialysis for at least 2 months OR you have diabetes with normal kidney function OR you are a healthy control You may NOT be eligible if: - You are on dialysis but not receiving erythropoietin (EPO) or iron treatment - Your haemoglobin (blood count) is outside the target range (110–130 g/L) - You have had recent blood loss or a blood transfusion - You have an active inflammatory illness - You have a solid organ cancer - You have unstable blood sugar control - You are pregnant Talk to your doctor about whether this trial might be right for you.