The Effect of Fish Oil Oral Supplementation on Fat Metabolism in Obese Subjects on a Weight Loss Diet.
The Effect of Oral Supplementation with n-3 Fatty Acid Ethyl Esters on Lipoprotein Metabolism in Obese Subjects on a Weight Loss Diet.
Professor Gerald Watts
30 participants
Oct 4, 2010
Interventional
Conditions
Summary
The aim of this study is to examine the effect of weight loss plus oral supplementation of Omacor (Fish Oil) on postprandial lipid and lipoprotein transport in obese subjects. We hypothesis that in obese subjects, triglyceride production will be further reduced with Omacor oral supplementation in addition to weight loss in the postprandial state. All eligible participants will be on a weight loss period for 12 weeks followed by a weight maintanence period of 4 weeks. During these 16 weeks, each participant will be randomised into either weight loss alone (Group 1) or weight loss plus Omacor oral supplementation (Group 2).
Eligibility
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Interventions
2 parallel groups. Group 1 - Weight loss alone. Participants will undergo 12 weeks of weight loss followed by 4 weeks of weight maintenance. Over the 16 weeks, each participant will meet with a dietitian face-to-face every 2 weeks (each session approximately 30-60minutes) for professional dietary advice. Group 2 - Weight loss plus Fish Oil. Participants will undergo 12 weeks of weight loss followed by 4 weeks of weight maintenance. Over the 16 weeks, each participant will meet with a dietitian face-to-face every 2 weeks (each session approximately 30-60minutes) for professional dietary advice. Throughout this 16 weeks period, participants will also be provided with n-3 fatty acid ethyl esters (Fish Oil) oral supplementation (4g/day) to be consumed daily.
Locations(1)
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ACTRN12610000750088