ActivePhase 2ACTRN12610001046099

Immune response to two-dose fractional inactivated poliovirus vaccine administered at 4- and 8- month of age

Immune response and seroconversion in two-dose fractional inactivated poliovirus vaccine administered at 4 and 8 months of age


Sponsor

World Health Organization

Enrollment

320 participants

Start Date

Jul 1, 2009

Study Type

Interventional

Conditions

Summary

The purpose of this study is to test the efficacy of a two dose schedule using either fractional or full dose IPV with the ultimate purpose to find a way for developing countries to adopt more affordable IPV use strategies in the future. It is hypothesized the fractional dose arm will be non-inferior to the full dose arm.


Eligibility

Sex: Both males and femalesMin Age: 4 MonthssMax Age: 5 Monthss

Plain Language Summary

Simplified for easier understanding

This study tests a fractional-dose polio vaccine given to healthy infants at 4 and 8 months of age to measure their immune response. Infants must be healthy, growing normally, and living within the study area. Families with immune deficiency conditions are not eligible.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

Two fractional 0.1 ml IPV doses administered intradermally at 4 and 8 month old infants

Two fractional 0.1 ml IPV doses administered intradermally at 4 and 8 month old infants


Locations(1)

camaguey, Cuba

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12610001046099


Related Trials