Does using progesterone reduce the miscarriage rate in high risk pregnancies?
In pregnant women with previous subfertility, does progesterone supplementation decrease the likelihood of miscarriage?
Dr Luke McLindon
344 participants
Jan 20, 2012
Interventional
Conditions
Summary
This project will assess the effect of progesterone therapy on pregnancy outcomes in women previously diagnosed with subfertility. It is hypothesised that progesterone supplementation in early pregnancy decreases the likelihood of miscarriage, and potentially late pregnancy complications in women with previous subfertility.
Eligibility
Inclusion Criteria2
- Previously diagnosed with subfertility (no pregnancy after 12 months random unprotected intercourse, a history of 3 or more miscarriages, failing to achieve an ongoing pregnancy after 12 months of random unprotected intercourse)
- Pregnancy less than 7 weeks + 0 days
Exclusion Criteria1
- Women who are pregnant as a result of Assisted Reproductive Technologies
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Progesterone pessary 400 mg, nightly until 12 weeks and 0 days, must be recruited prior to 7 weeks.
Locations(1)
View Full Details on ANZCTR
For the most up-to-date information, visit the official listing.
ACTRN12611000401954