RecruitingNCT06576622

PERIodontal Disease, Microbiota and Miscarriage

Status Report on Periodontal Status and Oral Microbiota Women Who Have Suffered Repeated Miscarriages: a Pilot Study


Sponsor

University Hospital, Toulouse

Enrollment

30 participants

Start Date

Nov 29, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and radiological examination (assessment carious, periodontal, mucosal and functional), which is part of the routine assessment in the service of odontology from Toulouse University Hospital. Saliva and subgingival plaque samples, classically carried out in routine dental surgery as part of the health check-up oral, will be used to carry out bacterial assays.


Eligibility

Sex: FEMALEMax Age: 18 Years

Inclusion Criteria2

  • women whom had repeated miscarriages
  • at least 6 natural teeth

Exclusion Criteria2

  • under antibiotic prebiotic or probiotics treatment one month prior to the study
  • with high infection risk (HIV,...)

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Interventions

OTHERbiological sampling

As part of the health check-up oral, Will be taken: * Salivary samples by sputum. * Samples of subgingival plaque in the periodontal sulcus * A collection of the history and disease risk factors will then be carried out. * periodontal problems by a routine care interview, the clinical examination and radiological examination.


Locations(1)

UH Toulouse

Toulouse, France

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NCT06576622


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