CompletedPhase 1ACTRN12611000671965

The Effect of Oxytocin on Cognitive Rigidity and Social Anxiety in Eating Disorders

The Effect of Oxytocin on Cognitive Rigidity and Social Anxiety in Eating Disorders: A Randomized Placebo Controlled Trial of Oxytocin in the Treatment of Anorexia Nervosa

Sponsor

The Centre for Eating and Dieting Disorders (CEDD)

Enrollment

80 participants

Start Date

Jan 6, 2012

Study Type

Interventional

Conditions

Anorexia Nervosa

Summary

The main purpose of this study is to ascertain whether inhaled oxytocin might have therapeutic potential in reducing the cognitive rigidity and social anxiety that have been shown to be important perpetuating factors in Anorexia Nervosa. Participants will be analysed to determine whether oxytocin brings about any improvements in thinking which might help patients with Anorexia Nervosa to recover more easily.

Eligibility

Sex: FemalesMin Age: 16 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests whether a single dose of oxytocin (a naturally occurring hormone) can reduce cognitive rigidity and social anxiety in females aged 16 and older with anorexia nervosa. These are two core features of eating disorders that are difficult to treat with standard approaches.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Oxytocin nasal spray - Participants will receive 2 daily doses of oxytocin (36 International Units per day) for the duration of the entire trial, 6 weeks. The oxytocin will be administered in 2 puffs, one to each nostril, twice a day, each puff containing 9 International Units of oxytocin.