CompletedEarly Phase 1ACTRN12611000679987

The effect of diet and portion size on oral fatty acid sensitivity

In overweight and obese subjects, will following a low-fat diet, or following a portion control diet, have an effect on oral fatty acid sensitivity.

Sponsor

Associate Professor Russell Keast

Enrollment

120 participants

Start Date

Apr 28, 2011

Study Type

Interventional

Conditions

Obesity Anxiety Diet

Summary

The primary purpose of this study is to investigate the effect of diet on people's ability to detect fatty acids in the oral cavity.

Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 75 Yearss

Plain Language Summary

Simplified for easier understanding

This study examines how diet and portion size affect the mouth's ability to detect fatty acids in adults aged 18-75 with a BMI over 20. Understanding oral fat sensitivity may help explain why some people are more prone to overeating high-fat foods.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

This group will follow a low-fat diet (25% total dietary fat from energy) for 6 weeks. The low-fat diet consists of subjects consuming 5 serves of vegetables per day, 2 serves of fruit per day, 3 serves of low-fat dairy per day, a maximum of 5 serves of carbohydrates (rice, pasta, bread etc) per day and a maximum of 3 serves of fats (butter oil, margarine etc) per day. Subjects are also given a list of foods to try and avoid, including fatty snacks like chips, biscuits cakes etc. Subjects will undergo a one on one dietary counseling session with the nutritionist where the diet they will be following will be explained to them, and questions they may have will be answered. This counseling session occurs once at the beginning of the study, but a weekly phone call will be made to subjects to give them the opportunity to ask questions throughout the 6 week period.