Obesity Clinical Trials

1,495 recruitingLast updated: June 17, 2026

There are 1,495 actively recruiting obesity clinical trials across 74 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1. Top locations include Houston, Texas, United States, New York, New York, United States, Chicago, Illinois, United States. Updated daily from ClinicalTrials.gov.


Obesity Trials at a Glance

1,495 actively recruiting trials for obesity are listed on ClinicalTrialsFinder across 6 cities in 74 countries. The largest study group is Not Applicable with 727 trials, with the heaviest enrollment activity in Houston, New York, and Chicago. Lead sponsors running obesity studies include Eli Lilly and Company, Novo Nordisk A/S, and Norwegian University of Science and Technology.

Treatments under study

About Obesity Clinical Trials

Looking for clinical trials for Obesity? There are currently 1,281 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Obesity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Obesity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,495 trials

Recruiting
Phase 1

A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body

ObesityHealthyOverweight
Boehringer Ingelheim80 enrolled1 locationNCT07407348
Recruiting
Phase 1

Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)

Obesity
Novo Nordisk A/S75 enrolled1 locationNCT07225816
Recruiting
Phase 1

A Study of LY3971297 in Healthy Participants

ObesityHypertensionHealthy
Eli Lilly and Company225 enrolled7 locationsNCT06148272
Recruiting
Not Applicable

Evaluation of the Care Pathway Offered by the "Chronic Disease Unit" to Obese Patients

Obesity
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer133 enrolled1 locationNCT06538220
Recruiting

Situation and Evolution of the Misuse of Alcohol and Other Addictive Behaviors in Obese Patients Being Managed at Nîmes University Hospital

Obesity
Centre Hospitalier Universitaire de Nīmes800 enrolled1 locationNCT04613791
Recruiting

Genetic, Microbiological and Behavioral Factors in Obesity

ObesityObesity, OverweightGenetics
Jan Kochanowski University200 enrolled2 locationsNCT07650149
Recruiting
Phase 2

Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity

ObesityOverweight
Kailera320 enrolled23 locationsNCT07497880
Recruiting

Diabetes and Heart Disease Risk in Blacks

ObesityCardiovascular DiseasesHypertension+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00001853
Recruiting
Phase 2

Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment

ObesityWeight LossEating+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)148 enrolled1 locationNCT00739362
Recruiting

Physical and Behavioral Traits of Overweight and Obese Adults

ObesityHealthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00428987
Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

ObesityCardiomyopathyLi-Fraumeni Syndrome+3 more
National Heart, Lung, and Blood Institute (NHLBI)5,000 enrolled3 locationsNCT01143454
Recruiting
Not Applicable

DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions

Obesity, OverweightAsthma (Diagnosis)Type 1 Diabetes+3 more
Adhera Health, Inc.280 enrolled1 locationNCT07638345
Recruiting
Phase 2

Phentermine's Impact on Treatment in Teens

Childhood Obesity
Russell McCulloh, MD240 enrolled2 locationsNCT07282340
Recruiting
Not Applicable

Daily Eating Patterns for Total Health Study

Obesity
The University of Tennessee, Knoxville174 enrolled1 locationNCT06455995
Recruiting
Not Applicable

Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose

ObesityHealthy Volunteer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)79 enrolled1 locationNCT06223555
Recruiting
Phase 1

A Study to Evaluate the Safety and Tolerability of Different Doses of CX11 Tablets

Obesity, Overweight
Corxel Pharmaceuticals90 enrolled2 locationsNCT07652047
Recruiting
Not Applicable

Michigan Weight Navigation Program (MiWeigh) Study

Obesity
University of Michigan500 enrolled1 locationNCT07465341
Recruiting
Phase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

ObesityObstructive Sleep Apnea
Amgen250 enrolled60 locationsNCT07225686
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-2232 in Participants With Obesity

Obesity
Alnylam Pharmaceuticals156 enrolled1 locationNCT07463846
Recruiting
Not Applicable

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

ObesityHealthy VolunteersNormal Physiology
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)120 enrolled1 locationNCT05545306