A low residue diet versus clear fluids prior to colonoscopy. The impact on bowel preparation quality and tolerability.
Dr Gregor Brown
250 participants
Jul 30, 2012
Interventional
Conditions
Summary
For a successful colonoscopy, good views of the bowel lining are essential. Ideally, a bowel cleansing preparation should be effective at cleaning out the bowel but should also be well tolerated with minimal abdominal discomfort, nausea or other adverse symptoms. Historically, oral intake on the day prior to colonoscopy has been limited to clear fluids alone - without food. Rather than a restriction to clear fluids, a low-residue diet may also result in good quality bowel preparation. This research project is aiming to determine whether there is any difference in the bowel cleansing quality or how well it is tolerated (such as the degree of hunger, nausea, interference with daily activities) between a standard dietary restriction to clear fluids and a low-residue diet (one that contains few indigestible components) on the day prior to colonoscopy.
Eligibility
Inclusion Criteria1
- participants who are undergoing outpatient colonoscopy for clinically accepted indications
Exclusion Criteria3
- Conditions generally considered as exclusions to colonoscopy in normal clinical practice. They are suspected bowel perforation, gastric outlet obstruction, toxic megacolon, severe colitis, and pregnancy or lactation.
- Significant renal failure (eGFR<30) or significant heart failure (New York Heart Association Class III or IV).
- History of phenylketonuria (PKU) or Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency and any person with a known hypersensitivity to a constituent of Movicol (Registered Trademark).
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Interventions
Low residue diet on the day prior to colonoscopy This commences at breakfast on the day prior to colonoscopy A low residue diet is one that contains few indigestible components. Foods allowed include such thing as cheese, white bread, pasta and vanilla ice cream among others
Locations(1)
View Full Details on ANZCTR
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ACTRN12612000481875