Mometasone irrigation in the treatment of chronic rhinosinusitis

This study tests whether rinsing the nasal passages with a solution that contains a steroid medication (mometasone) is more effective than the usual steroid nasal spray after sinus surgery for chronic rhinosinusitis (long-term sinus inflammation). Patients who have sinus surgery are randomly assigned to use either the mometasone rinse or a plain salt water rinse, and neither the patient nor the surgeon knows which treatment is being used. You may be eligible if: - You are 18 years or older - You have chronic rhinosinusitis (nasal symptoms for over 12 weeks with or without nasal polyps) - You are scheduled for endoscopic sinus surgery (keyhole sinus surgery) You may NOT be eligible if: - You are under 18 years old - You are pregnant - You have a known sensitivity to mometasone - You are unable to give informed consent due to age, mental illness, or communication problems Talk to your doctor about whether this trial might be right for you.