Comparison of the efficacy and safety of adapalene versus benzoyl peroxide in the treatment of mild acne vulgaris; a clinical trial
A randomized, double-blind, clinical trial to compare the efficacy (lesion number), side effects, and patient's satisfaction rate of topical adapalene and benzoyl peroxide in the cases with mild acne vulgaris
Dr Shahla Talghini
60 participants
Jan 1, 2011
Interventional
Conditions
Summary
The present clinical trial aims to compare the efficacy and safety profile of topical adapalene 0.1% and BPO 2.5% gels in patients with mild acne vulgaris. For this purpose, 60 patients equally received either topical adapalene 0.1% gel or topical BPO 2.5% gel once daily to the entire face (except periocular area and lip) for two consecutive months. Three months later, number of lesions, side effects and patients' satisfaction were compared between the two groups.
Eligibility
Inclusion Criteria2
- Diagnosis of acne vulgaris
- Mild disease according to the Evaluator Global Severity Score (grade 2)
Exclusion Criteria4
- Severe acne vulgaris
- Any dermatologic conditions requiring systemic therapy
- Nursing/pregnant women
- The women were planning for pregnancy
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Interventions
Patients received topical adapalene 0.1% gel (ADA; Differin; Galderma, Watford, UK) once daily for 8 weeks.
Locations(1)
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ACTRN12612001006831