Intraoperative fluid optimization of patients undergoing total hip or knee arthroplasty using pulse pressure variation obtained by a continuous noninvasive blood pressure monitor
The influence of fluid optimization using pulse pressure variation obtained by continuous noninvasive blood pressure monitor compared to standard perioperative pressure driven fluid management in the patients undergoing total hip or knee replacement under general anesthesia on the postoperative morbidity (number and rate of complications and length of stay)
Dpt. of Anesthesia and Intensive Care of The Faculty of Medicine Plzen - Charles University Prague)
80 participants
Oct 1, 2012
Interventional
Conditions
Summary
Aim of the trial is to evaluate the possibility of goal-directed fluid therapy during major orthopedic procedures under general anesthesia using protocol based on pulse pressure variation obtained by noninvasive continuous arterial pressure monitoring in comparison to standard usually given care. Influence on the postoperative outcome (number and rate of complications and hospital length of stay) will be assessed.
Eligibility
Inclusion Criteria1
- elective hip or knee arthroplasty, general anesthesia, regular heart rhythm, given and signed informed consent
Exclusion Criteria1
- obvious perfusion abnormality on the side of measurement, vascular implants on the side of measurement, known neuronal or neuromuscular disease of upper extremities, peripheral edema
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Interventions
Fluid optimization guided by the pulse pressure variation obtained by continuous noninvasive arterial pressure monitor (CNAP) based on the volume clamp method in addition to standard pressure/clinical signs based fluid management during the surgical procedure.
Locations(1)
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ACTRN12612001014842