RecruitingNot ApplicableNCT07198282

The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery

The Effect of Different Flap Closure Techniques on Postoperative Morbidity: A Randomized Controlled Trial for Impacted Third Molar Surgery


Sponsor

Recep Tayyip Erdogan University

Enrollment

148 participants

Start Date

Feb 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

1\. ABSTRACT This study is a randomized controlled trial comparing the clinical efficacy and safety of four different flap closure techniques in reducing postoperative morbidity (pain, swelling, trismus, wound healing) and improving patient quality of life (GOHAI) following impacted mandibular third molar extraction. The methods include conventional suturing, sutureless technique, surgical drain, and cyanoacrylate tissue adhesive, which are commonly used in oral surgery practice. The study aims to scientifically evaluate the effects of each method on patients and to determine the most appropriate clinical approach.


Eligibility

Min Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This randomized controlled trial compares four different wound closure methods used after surgical removal of impacted lower wisdom teeth: conventional stitches (silk sutures), a sutureless technique (letting the wound heal on its own), a surgical drain, and a cyanoacrylate tissue adhesive (medical-grade glue). The study measures how each method affects pain, swelling, jaw stiffness, wound healing, and quality of life in the days following surgery. Healthy adults aged 18–40 with no systemic diseases, whose impacted wisdom teeth are in a specific position requiring surgical extraction, are eligible; pregnant women, patients on blood thinners, those with coagulation disorders, and heavy smokers or alcohol users are excluded. Participation involves the wisdom tooth extraction, being assigned to one of four closure methods, and follow-up visits on days 2 and 7 after surgery. This summary was prepared as patient-facing educational content using AI assistance.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREConventional Suturing

Wound edges are approximated using 3/0 braided, non-absorbable silk sutures (Doğsan®, Turkey). Standard oral surgery closure technique.

PROCEDURESutureless Technique

The wound is left to heal by secondary intention without using any suturing material.

PROCEDURESurgical Drain

A biocompatible sterile plastic drain is placed in the surgical site to facilitate drainage of blood and fluids, helping to reduce edema and hematoma formation.

PROCEDURECyanoacrylate Tissue Adhesive

Cyanoacrylate-based medical tissue adhesive (PeriAcryl®90 High Viscosity) is applied to the wound edges, providing rapid polymerization and effective closure.


Locations(1)

Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery

Rize, Rize Province, Turkey (Türkiye)

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NCT07198282


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