Non-surgical outcomes among older adults after total joint replacement.
Neuropsychological and affective outcomes among older adults after total joint replacement.
Prof Jane L. Mathias
60 participants
Jan 31, 2013
Observational
Conditions
Summary
This study aims to examine the incidence of cognitive and affective problems after joint replacement surgery. These outcomes will also be placed into context of post-surgical pain and quality of life. The potential moderating role of cognitive reserve will also be assessed. The specific aims of the study are to: a) Define the incidence of short- and long-term cognitive dysfunction, depression and anxiety following joint replacement surgery. b) Determine the potential moderating role of reserve on these poorer outcomes. c) Identify the predictors of these poorer outcomes, with specific reference to quality of life, pain, and chronic medical conditions
Eligibility
Inclusion Criteria5
- Joint replacement patients
- Undergoing primary total hip or knee replacement
- Aged 50 or over
- Proficient in English
- Controls
Exclusion Criteria8
- Aged 50 or over
- Proficient in English
- Joint replacement patients:
- Undergoing revision surgery, partial replacement or any other type of joint surgery.
- Have an existing neurological condition (e.g. dementia, multiple sclerosis), that is likely to affect performance on a cognitive battery
- Controls:
- Have had invasive surgery (minimally invasive is acceptable) within the previous 6 months or have surgery planned for the following six months
- Have an existing neurological condition that is likely to affect performance on a cognitive battery
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Interventions
Participants are older adults who are undergoing standard care total hip and knee replacement. They will be assessed on three occasions: approx 2 weeks pre-surgery, 2 weeks post-surgery, 6 months post-surgery. They will be assessed on their cognitive function(baseline and 2nd follow-up only), depression, anxiety, quality of life, pain and cognitive reserve (baseline only).
Locations(1)
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ACTRN12613000177752