RecruitingACTRN12613000177752

Non-surgical outcomes among older adults after total joint replacement.

Neuropsychological and affective outcomes among older adults after total joint replacement.


Sponsor

Prof Jane L. Mathias

Enrollment

60 participants

Start Date

Jan 31, 2013

Study Type

Observational

Conditions

Summary

This study aims to examine the incidence of cognitive and affective problems after joint replacement surgery. These outcomes will also be placed into context of post-surgical pain and quality of life. The potential moderating role of cognitive reserve will also be assessed. The specific aims of the study are to: a) Define the incidence of short- and long-term cognitive dysfunction, depression and anxiety following joint replacement surgery. b) Determine the potential moderating role of reserve on these poorer outcomes. c) Identify the predictors of these poorer outcomes, with specific reference to quality of life, pain, and chronic medical conditions


Eligibility

Sex: Both males and femalesMin Age: 50 Yearss

Plain Language Summary

Simplified for easier understanding

This study is looking at what happens to older adults' memory, mood, and quality of life after they have a hip or knee replacement. While joint replacement surgery is very common and generally very successful at reducing pain, some patients notice changes in their thinking or emotional wellbeing afterwards. Researchers want to understand how often this happens, what predicts it, and how well the brain's natural reserve can protect against these effects. You may be eligible if: - You are 50 years of age or older - You are having your first (primary) total hip or knee replacement, OR you are a partner, close friend, or sibling of someone who is - You are proficient in English You may NOT be eligible if: - You are having revision surgery, partial replacement, or another type of joint surgery - You have a neurological condition likely to affect thinking (e.g. dementia, multiple sclerosis) - (For controls) You have had invasive surgery in the last 6 months or have surgery planned in the next 6 months Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Participants are older adults who are undergoing standard care total hip and knee replacement. They will be assessed on three occasions: approx 2 weeks pre-surgery, 2 weeks post-surgery, 6 months pos

Participants are older adults who are undergoing standard care total hip and knee replacement. They will be assessed on three occasions: approx 2 weeks pre-surgery, 2 weeks post-surgery, 6 months post-surgery. They will be assessed on their cognitive function(baseline and 2nd follow-up only), depression, anxiety, quality of life, pain and cognitive reserve (baseline only).


Locations(1)

Repatriation Hospital - Daw Park

SA, Australia

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ACTRN12613000177752


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