Not Yet RecruitingPhase 4ACTRN12613000314729

Subconjunctival dexamethasone in routine cataract surgery

A study comparing the postoperative outcomes of cataract surgeries with and without the use of subconjunctival dexamethasone


Sponsor

The Alfred

Enrollment

240 participants

Start Date

Apr 1, 2013

Study Type

Interventional

Conditions

Summary

For many years, some eye surgeons have given patients having cataract surgery an injection of dexamethasone (a type of cortisone or steroid) into the surface of the eye (subconjunctival) at the end of surgery. Dexamethasone is approved in Australia to treat inflammation of the eye during and following eye surgery. Some surgeons believe the injections are not needed because: 1. The steroid drops are usually enough to help the eye recover 2. The injection can occasionally hurt Others surgeons use the injection because: 1. It seems to makes patients’ eyes more comfortable for the first few days after surgery 2. It may help vision to improve faster after surgery by reducing the risk of macular oedema (swelling of the central part of the retina) This study will not determine whether a patient receives a dexamethasone injection but will look at the outcomes of surgery. From this, we hope to show how useful it is to give a subconjunctival injection of dexamethasone at the time of cataract surgery.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Inclusion Criteria1

  • Patients with visually debilitating cataracts requiring surgery

Exclusion Criteria1

  • Patients with a history of other ocular pathologies or other abnormal ocular examinations

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Interventions

The administration of a single dose (1ml) of subconjunctival dexamethasone (4mg/ml) injection at the end of uncomplicated cataract surgery. We will examine the amount of post-operative intraocular inf

The administration of a single dose (1ml) of subconjunctival dexamethasone (4mg/ml) injection at the end of uncomplicated cataract surgery. We will examine the amount of post-operative intraocular inflammation and macular oedema following surgery for 1 month post-surgery


Locations(1)

The Alfred - Prahran

VIC, Australia

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ACTRN12613000314729


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