CompletedPhase 2ACTRN12614000003673

A single-blind randomised controlled trial of topical Kanuka honey for the treatment of Acne

In adult patients with Acne will topical medical grade Kanuka honey, in addition to washing with Protex Soap Fresh Antibacterial, reduce acne severity compared with washing with Protex Soap Fresh Antibacterial alone.


Sponsor

Honeylab Ltd

Enrollment

138 participants

Start Date

Feb 4, 2014

Study Type

Interventional

Conditions

Summary

A recent pilot study using a Kanuka honey product for Acne showed that over 80% of participants self reported improvement, therefore this study treatment has the potential to be an effective treatment for Acne symptoms. In this study 138 adults with Acne will either wash their face with Protex Soap Fresh Antibacterial alone twice daily, or apply topical Kanuka honey to areas of Acne on their face for 30-60 minutes twice a day prior to washing with Protex Soap Fresh Antibacterial for 12 weeks. At baseline and after 4 weeks and 12 weeks the patient's Acne will be assessed to look at changes in severity. Participants will complete a diary for 12 weeks to record their daily treatment applications and weekly severity assessment. Subjects will complete a Dermatology Quality of Life questionnaire at all visits, to note any changes in quality of life. A visual analogue scale will be completed to note any improvement or worsening of a patient's Acne at Visits 2 and 3. This study will investigate the effectiveness of Kanuka honey in treating Acne, potentially improving the health outcomes of those with the condition, and will contribute to the knowledge base around the use of honey for the treatment of skin conditions.


Eligibility

Sex: Both males and femalesMin Age: 16 YearssMax Age: 40 Yearss

Plain Language Summary

Simplified for easier understanding

This study is testing whether a topical cream containing Kanuka honey can treat acne. Acne is a very common skin condition affecting teenagers and adults. Researchers are comparing the honey cream to a standard soap-based wash to see if it can reduce pimples and skin inflammation. You may be eligible if: - You are between 16 and 40 years old - Your acne severity score (IGA) is rated 2 or higher by an investigator You may NOT be eligible if: - You have a significant systemic illness - You have used oral steroids or oral antibiotics for acne in the last 4 weeks - You are currently using topical steroids or topical antibiotics for acne - You have changed your oral contraceptive in the last 3 months - You have used a systemic retinoid in the past 2 months - You have a known or suspected allergy to honey Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Topical medical grade Kanuka honey with 10% glycerin content applied to the affected facial area twice daily for 30-60 minutes per application, for twelve weeks. Patients will then wash area with Pro

Topical medical grade Kanuka honey with 10% glycerin content applied to the affected facial area twice daily for 30-60 minutes per application, for twelve weeks. Patients will then wash area with Protex Soap Fresh Antibacterial medicated soap as per manufacturer's instructions, twice daily after honey treatment. A patient diary will record applications during the treatment period.


Locations(1)

New Zealand

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